Breast ; Biopsy ; Ultrasound guidance ; Breast cancer diagnosis
Abstract
Purpose: To determine the diagnostic accuracy, underestimation rate and false negative rate of
sonographically guided core needle biopsy for breast lesions.
Materials and Methods: We included 1,221 breast lesions from 1,073 patients who had undergone
sonographically guided 14-gauge core needle biopsies between January 2017 and December
2017. The sonographic category of breast lesions and the pathologic results of core needle
biopsies were reviewed and correlated with that of surgery or vacuum assisted biopsy, or >1yr
follow-up. The positive predictive value for each category, sensitivity, underestimation rate and
false negative rate of core needle biopsy were evaluated.
Results: The positive predictive values for each sonographic category were as follows: 0% in category 2;
0% in category 3; 14.3% in category 4a; 51.5% in category 4b; 86.4% in category 4c and 99.0%
in category 5. The sensitivity of core needle biopsy was 94.9% (462/487). The underestimation
rate was 13.0% (23/177) for high-risk and 40.4% (37/94) for ductal carcinoma in situ. The false
negative rate was 0.3% (2/581).
Conclusion: Sonographically guided core needle biopsy for 2017 year in our hospital was accurate
diagnostic tool for evaluating breast lesion.