Adolescent ; Adult ; Biopsy ; Bone Neoplasms/diagnosis* ; Bone Neoplasms/pathology ; Bone and Bones/pathology ; Chondroblastoma/diagnosis* ; Chondroblastoma/pathology ; Contrast Media ; Female ; Gadolinium DTPA ; Humans ; Magnetic Resonance Imaging*/instrumentation ; Magnetic Resonance Imaging*/methods ; Magnetic Resonance Imaging*/statistics & numerical data ; Male ; Retrospective Studies
Abstract
PURPOSE: The purpose of this study was to describe the MR findings of chondroblastoma with pathologic correlation.
METHOD: In 22 patients with pathologically proven chondroblastoma, MR signal characteristics were correlated with pathological findings.
RESULTS: On T2-weighted images, 12 (55%) lesions were hyperintense with hypointense areas in 9 lesions, whereas 10 (45%) were hypointense. Therefore, 19 of 22 (86%) lesions with pathologic correlation had hypointense areas entirely (n = 10) or partly (n = 9) on T2-weighted images. On gadolinium-enhanced images, 13 (59%) lesions showed lobular enhancement and 9 (41%) showed marginal and septal enhancement. Low signal intensity on T2-weighted MR images was most strongly associated with an abundance of immature chondroid matrix, hypercellularity of the chondroblasts, calcifications, and hemosiderin on histology.
CONCLUSION: Chondroblastoma was found to show hypointense portions on T2-weighted images. Signal intensity on T1- and T2-weighted MR images in chondroblastoma was dependent on the amounts of histopathological components.