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Impact of the Total Number of Carotid Plaques on the Outcome of Ischemic Stroke Patients with Atrial Fibrillation

DC FieldValueLanguage
dc.contributor.author김영대-
dc.contributor.author남효석-
dc.contributor.author박형종-
dc.contributor.author유준상-
dc.contributor.author이혜선-
dc.contributor.author허지회-
dc.date.accessioned2019-12-18T01:23:23Z-
dc.date.available2019-12-18T01:23:23Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/173497-
dc.description.abstractBACKGROUND: Atrial fibrillation (AF) shares several risk factors with atherosclerosis. We investigated the association between total carotid plaque number (TPN) and long-term prognosis in ischemic stroke patients with AF. METHODS: A total of 392 ischemic stroke patients with AF who underwent carotid ultrasonography were enrolled. TPN was assessed using B-mode ultrasound. The patients were categorized into two groups according to best cutoff values for TPN (TPN ≤ 4 vs. TPN ≥ 5). The long-term risk of major adverse cardiovascular events (MACE) and mortality according to TPN was investigated using a Cox hazard model. RESULTS: After a mean follow-up of 2.42 years, 113 patients (28.8%) had developed MACE and 88 patients (22.4%) had died. MACE occurred more frequently in the TPN ≥ 5 group than in the TPN ≤ 4 group (adjusted hazard ratio [HR], 1.50; 95% confidence interval [CI], 1.01-2.21; p < 0.05). Moreover, the TPN ≥ 5 group showed an increased risk of all-cause mortality (adjusted HR, 2.69; 95% CI, 1.40-5.17; p < 0.05). TPN along with maximal plaque thickness and intima media thickness showed improved prognostic utility when added to the variables of the CHAD2DS2-VASc score. CONCLUSION: TPN can predict the long-term outcome of ischemic stroke patients with AF. Adding TPN to the CHAD2DS2-VASc score increases the predictability of outcome after stroke.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleImpact of the Total Number of Carotid Plaques on the Outcome of Ischemic Stroke Patients with Atrial Fibrillation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.googleauthorHyungjong Park-
dc.contributor.googleauthorMinho Han-
dc.contributor.googleauthorYoung Dae Kim-
dc.contributor.googleauthorJoonsang Yoo-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorJin Kyo Choi-
dc.contributor.googleauthorJi Hoe Heo-
dc.contributor.googleauthorHyo Suk Nam-
dc.identifier.doi10.3390/jcm8111897-
dc.contributor.localIdA00702-
dc.contributor.localIdA01273-
dc.contributor.localIdA01273-
dc.contributor.localIdA05600-
dc.contributor.localIdA05600-
dc.contributor.localIdA02513-
dc.contributor.localIdA02513-
dc.contributor.localIdA03312-
dc.contributor.localIdA03312-
dc.contributor.localIdA04369-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.identifier.pmid31703280-
dc.subject.keywordatrial fibrillation-
dc.subject.keywordcarotid stenosis-
dc.subject.keywordcerebral infarction-
dc.subject.keywordoutcomes-
dc.subject.keywordultrasonography-
dc.contributor.alternativeNameKim, Young Dae-
dc.contributor.affiliatedAuthor김영대-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor박형종-
dc.contributor.affiliatedAuthor박형종-
dc.contributor.affiliatedAuthor유준상-
dc.contributor.affiliatedAuthor유준상-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor허지회-
dc.contributor.affiliatedAuthor허지회-
dc.citation.volume8-
dc.citation.number11-
dc.citation.startPageE1897-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.8(11) : E1897, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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