0 59

Cited 0 times in

Brachial-ankle pulse wave velocity for predicting functional outcomes in patients with cryptogenic stroke

Authors
 Minho Han  ;  Young Dae Kim  ;  Hyung Jong Park  ;  In Gun Hwang  ;  Junghye Choi  ;  Jimin Ha  ;  Ji Hoe Heo  ;  Hyo Suk Nam 
Citation
 JOURNAL OF CLINICAL NEUROSCIENCE, Vol.69 : 214-219, 2019 
Journal Title
 JOURNAL OF CLINICAL NEUROSCIENCE 
ISSN
 0967-5868 
Issue Date
2019
Keywords
Brachial-ankle pulse wave velocity ; Cryptogenic stroke ; Prognosis ; Stroke
Abstract
Even after extensive standard evaluation, the probable cause of stroke in some patients remains unclear; this condition is defined as cryptogenic stroke (CS). The prognosis of patients with CS is largely undetermined. We investigated whether higher brachial-ankle pulse wave velocities (baPWVs) can predict poor functional outcomes at 3 months after stroke onset in these patients. We investigated patients with CS with first-ever acute cerebral infarction who underwent baPWV measurements. The stroke subtypes were classified using the Trial of ORG 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale scores of >2 at 3 months after stroke onset. In total, 595 patients with CS were included; among them, 360 were men (60.5%). Their mean age was 65.0 ± 12.4 years. One-hundred-eleven patients (18.7%) had poor functional outcomes. In the multivariable logistic regression analysis, the cutoff baPWV value based on the receiver-operating characteristic curve was >1968 cm/s, which was determined as a strong independent predictor (OR 3.159, 95% CI 1.487-6.715, p = 0.003). The OR of the cutoff value was higher in the patients with CS with initial National Institutes of Health Stroke Scale (NIHSS) scores of ≥5 (OR 4.252, 95% CI 1.596-11.324, p = 0.004); that in the patients with initial NIHSS scores of <5 was not significant (OR 1.671, 95% CI 0.620-4.505, p = 0.310). baPWV measurement during the acute stroke phase might be useful in identifying patients with CS at high risks of having a poor neurological prognosis.
Full Text
https://www.sciencedirect.com/science/article/pii/S0967586819308859
DOI
10.1016/j.jocn.2019.07.050
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Dae(김영대) ORCID logo https://orcid.org/0000-0001-5750-2616
Nam, Hyo Suk(남효석) ORCID logo https://orcid.org/0000-0002-4415-3995
Park, Hyungjong(박형종)
Heo, Ji Hoe(허지회) ORCID logo https://orcid.org/0000-0001-9898-3321
Hwang, In Gun(황인건) ORCID logo https://orcid.org/0000-0002-5193-4060
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/173494
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse