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유방암의 출력 도플러 초음파 소견: 병리학적 미세혈관 정도 및 림프절 전이와 비교

Other Titles
 Power Doppler Ultrasound of Breast Cancer: Correlation with Histologic Microvessel Density and Lymph Node Metastasis 
 김은경  ;  이용희  ;  손홍주  ;  오기근  ;  정현철  ;  이경식 
 Journal of the Korean Society of Medical Ultrasound (대한초음파의학회지), Vol.19(4) : 319-323, 2000 
Journal Title
 Journal of the Korean Society of Medical Ultrasound (대한초음파의학회지) 
Issue Date
Breast neoplasms (US) ; Ultrasound (US) ; Doppler studies
PURPOSE : To evaluate how breast cancer vascularity detected by power Doppler sonography correlates with microvessel density(MVD) and lymph node involvement. MATERIALS and METHODS : Power Doppler US was performed on 47 patients with pathologically diagnosed invasive ductal carcinoma. According to the presense or absence of vessels, power Doppler findings were categorized regarding total tumors and tumors less than 2cm. MVD was assessed immunohistochemically using polyclonal antisera against factor VIII. Tumor vascularity was correlated with MVD and lymph node involvement. RESULTS : Among 47 infiltrating ductal carcinomas, 35(74.5%) cases were vascular and 12(25.5%) cases were avascular on power Doppler US. The mean MVD of the vascular and avascular carcinomas did not show any statistical difference. However, lymph mode involvement showed significant statistical difference between the two groups (51.4% versus 25.0%, p=0.036), even though in cancers less than 2cm (40% versus 22.2%, p=0.047). CONCLUSION : Breast cancer vascularity detected by power Doppler sonography was not correlated with MVD but correlated with lymph node involvement. So we suggest that power Doppler sonography may be useful for predicting lymph node metastasis.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Chung, Hyun Cheol(정현철) ORCID logo https://orcid.org/0000-0002-0920-9471
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