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Test-bolus injection for optimization of arterial phase imaging during contrast-enhanced hepatic MR imaging.

 Jeong-Sik Yu  ;  Ki Whang Kim  ;  Byung-June Jo  ;  Mi-Gyoung Jeong  ;  Jai Keun Kim  ;  Jin Kyeung Hahm  ;  Jong Tae Lee  ;  Hyung Sik Yoo 
 Yonsei Medical Journal, Vol.41(4) : 459-467, 2000 
Journal Title
Issue Date
Adult ; Aged ; Aged, 80 and over ; Female ; Hepatic Artery/pathology ; Humans ; Image Enhancement* ; Liver/pathology* ; Liver Neoplasms/diagnosis ; Liver Neoplasms/secondary ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Time Factors
Liver MR ; liver neoplasms ; contrast enhancement MR
Contrast enhancement during the dynamic MR imaging is important for the detection and characterization of focal liver lesions. The purpose of this study was to determine whether or not a timing examination with a injection of a 1.0-mL bolus of gadopentetate dimeglumine into the antecubital vein followed by rapid dynamic scanning and measurement of signal intensity of the aorta could help to obtain proper arterial-dominant phase images for the characterization of focal hepatic lesions during subsequent multiphase dynamic MR imaging. The imaging delay to acquisition of the first gadolinium-enhanced image for multiphase dynamic MR imaging was set to equal the time to peak aortic enhancement during the test examination. The first contrast-enhanced images of 80 patients with 160 focal liver lesions (hepatocellular carcinoma, n = 79; cavernous hemangioma, n = 51; metastatic tumor, n = 30) were then retrospectively reviewed. Peak aortic enhancement occurred between 10 and 28 seconds (mean, 16.5 seconds +/- 3.1) after starting the infusion of contrast material in 80 patients during the test-examination. Depending on the findings of intrahepatic vascular enhancement on the full-scale dynamic images, hepatic arterial phase (n = 11, 14%) or sinusoid phase (n = 65, 81%) imaging was obtained during the first gadolinium-enhanced acquisition in 76 (95%) of 80 patients. Three different lesions were well characterized and easily distinguished from each other (p < .0001) on the first-phase images depending on their enhancement pattern. In the majority of patients, timing examination with test-bolus injection was helpful in obtaining qualified images for the characterization of various focal lesions.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Yu, Jeong Sik(유정식) ORCID logo https://orcid.org/0000-0002-8171-5838
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