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Renal Artery Embolization Using a New Liquid Embolic Material Obtained by Partial Hydrolysis of Polyvinyl Acetate (Embol): Initial Experience in Six Patients

Authors
 Sung Il Park  ;  Do Yun Lee  ;  Jong Yoon Won  ;  Sangsoo Park 
Citation
 Korean Journal of Radiology, Vol.1(3) : 121-126, 2000 
Journal Title
KOREAN JOURNAL OF RADIOLOGY
ISSN
 1229-6929 
Issue Date
2000
MeSH
Aged ; Aneurysm, False/therapy ; Angiomyolipoma/therapy ; Carcinoma, Renal Cell/therapy ; Child ; Embolization, Therapeutic* ; Ethanol ; Female ; Humans ; Iohexol/analogs & derivatives* ; Kidney Neoplasms/therapy* ; Male ; Middle Aged ; Polyvinyls/therapeutic use ; Renal Artery*
Keywords
Arteries, therapeutic blockade ; Embolism, therapeutic ; Kidney, interventional procedure ; Interventional procedures, technology
Abstract
Objective

To evaluate the therapeutic efficacy of a new liquid embolic material, Embol, in embolization of the renal artery.


Materials and Methods

Embol is a new embolic material obtained by partial hydrolysis of polyvinyl acetate mixed in absolute ethanol and Iopromide 370 and manufactured by Schering Korea, Kyonggido, Korea. Six patients who underwent embolization of the renal artery using Embol were evaluated. Four were male and two were female and their ages ranged from 11 to 70 (mean, 53) years. Clinical and radiologic diagnoses referred for renal artery embolization were renal cell carcinoma (n = 3), renal angiomyolipoma (n = 2) and pseudoaneurysm of the renal artery (n = 1). After selective renal angiography, Embol was injected through various catheters, either with or without a balloon occlusion catheter. Changes in symptoms and blood chemistry which may have been related to renal artery embolization with Embol were analyzed.


Results

The six patients showed immediate total occlusion of their renal vascular lesions. One of the three in whom renal cell carcinoma was embolized with Embol underwent radical nephrectomy, and the specimen thus obtained revealed 40% tumor necrosis. In the two patients with angiomyolipomas, the tumors decreased in size and abdominal pain subsided. Bleeding from pseudoaneurysm of the renal artery was successfully controlled. Four patients showed symptoms of post-embolization syndrome, and one of these also showed increased levels of blood urea nitrogen and creatinine. One patient experienced transient hypertension.


Conclusion

Embol is easy to use, its radiopacity is adequate and it is a safe and effective embolic material which provides immediate and total occlusion of renal vascular lesions.
Files in This Item:
T200001885.pdf Download
DOI
10.3348/kjr.2000.1.3.121
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Do Yun(이도연)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/171792
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