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Value of CT added to ultrasonography for the diagnosis of lymph node metastasis in patients with thyroid cancer

Authors
 Younghen Lee  ;  Ji-hoon Kim  ;  Jung Hwan Baek  ;  So Lyung Jung  ;  Sun-Won Park  ;  Jinna Kim  ;  Tae Jin Yun  ;  Eun Ju Ha  ;  Kyu Eun Lee  ;  Soon Young Kwon  ;  Kyung-Sook Yang  ;  Dong Gyu Na 
Citation
 Head & Neck, Vol.40(10) : 2137-2148, 2018 
Journal Title
 Head & Neck 
ISSN
 1043-3074 
Issue Date
2018
Keywords
CT ; lymph node ; metastasis ; thyroid cancer ; ultrasonography
Abstract
BACKGROUND: The benefit of CT for the diagnosis of lymph node metastasis in patients with thyroid cancer is still unclear. METHODS: Three hundred fifty-one patients with thyroid cancers from 7 hospitals were prospectively enrolled in order to compare diagnostic performance between a combination of ultrasound and CT (ultrasound/CT) and ultrasound alone for prediction of lymph node metastasis and to calculate patient-based benefits of CT added to ultrasound. RESULTS: Of 801 pathologically proven neck levels, ultrasound/CT showed higher sensitivities in both central and lateral compartments and improved accuracy in the lateral compartment compared to ultrasound alone. In the retropharyngeal/superior mediastinal compartment, although CT could detect lymph node metastasis an ultrasound could not. Patient-based benefit was demonstrated in 13.1% of patients (46/351), and was higher in patients with cancers >1 cm than cancers ≤1 cm. CONCLUSION: In patients with thyroid cancer, CT improved surgical planning by enhancing the sensitivity for lymph node metastasis and by detecting lymph node metastasis that was overlooked with ultrasound alone.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1002/hed.25202
DOI
10.1002/hed.25202
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jinna(김진아) ORCID logo https://orcid.org/0000-0002-9978-4356
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/170858
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