Cited 23 times in
Novel anti-biofouling light-curable fluoride varnish containing 2-methacryloyloxyethyl phosphorylcholine to prevent enamel demineralization
DC Field | Value | Language |
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dc.contributor.author | 권재성 | - |
dc.contributor.author | 김광만 | - |
dc.contributor.author | 김도현 | - |
dc.contributor.author | 장성일 | - |
dc.contributor.author | 최성환 | - |
dc.contributor.author | 황충주 | - |
dc.date.accessioned | 2019-03-15T02:25:00Z | - |
dc.date.available | 2019-03-15T02:25:00Z | - |
dc.date.issued | 2019 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167452 | - |
dc.description.abstract | We evaluated the efficacy of light-curable fluoride varnish (LCFV) that contains 2-methacryloyloxyethyl phosphorylcholine (MPC) in terms of anti-biofouling properties and prevention of tooth enamel demineralization. MPC was mixed with and incorporated into LCFV at 0 (control), 1.5, 3.0, 5.0, 10.0, 20.0, and 40.0 weight percentage (wt%). Addition of high wt% of MPC resulted in increased film thickness and decreased the degree of conversion, indicating loss of the advantageous properties of LCFV. Addition of 1.5, 3, or 5 wt% MPC significantly reduced the amount of bovine serum albumin adsorbed from a solution and proteins adsorbed from brain heart infusion medium compared to the control (P < 0.001). A similar pattern was observed for bacterial adhesion: significantly less Streptococcus mutans cells adhered on the surface of LCFV with 1.5, 3, or 5 wt% MPC (P < 0.001) than on the control, and similar results were obtained for Actinomyces naeslundii and Streptococcus sanguinis adherence to LCFV with 3 wt% MPC. Finally, bacterial adhesion, surface microhardness loss, and the depth of demineralization were substantially lower on bovine tooth enamel surface coated with LCFV containing 3 wt% of MPC than in the control treatment (0 wt% MPC). Therefore, this novel LCFV containing a low concentration of MPC (e.g., 3 wt%) would be effective in anti-biofouling while maintaining the important advantageous features of light-curable fluoride in preventing demineralization. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Novel anti-biofouling light-curable fluoride varnish containing 2-methacryloyloxyethyl phosphorylcholine to prevent enamel demineralization | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) | - |
dc.contributor.googleauthor | Jae-Sung Kwon | - |
dc.contributor.googleauthor | Myung-Jin Lee | - |
dc.contributor.googleauthor | Ji-Young Kim | - |
dc.contributor.googleauthor | Dohyun Kim | - |
dc.contributor.googleauthor | Jeong-Hyun Ryu | - |
dc.contributor.googleauthor | Sungil Jang | - |
dc.contributor.googleauthor | Kwang-Mahn Kim | - |
dc.contributor.googleauthor | Chung-Ju Hwang | - |
dc.contributor.googleauthor | Sung-Hwan Choi | - |
dc.identifier.doi | 10.1038/s41598-018-38255-2 | - |
dc.contributor.localId | A00247 | - |
dc.contributor.localId | A00312 | - |
dc.contributor.localId | A00389 | - |
dc.contributor.localId | A03440 | - |
dc.contributor.localId | A04083 | - |
dc.contributor.localId | A04492 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 30723241 | - |
dc.contributor.alternativeName | Kwon, Jae-Sung | - |
dc.contributor.affiliatedAuthor | 권재성 | - |
dc.contributor.affiliatedAuthor | 김광만 | - |
dc.contributor.affiliatedAuthor | 김도현 | - |
dc.contributor.affiliatedAuthor | 장성일 | - |
dc.contributor.affiliatedAuthor | 최성환 | - |
dc.contributor.affiliatedAuthor | 황충주 | - |
dc.citation.volume | 9 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1432 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.9(1) : 1432, 2019 | - |
dc.identifier.rimsid | 48799 | - |
dc.type.rims | ART | - |
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