0 110

Cited 0 times in

Ablation Volume Measurement After Percutaneous Cryoablation Using a Two-cryo-probe Technique for Small Hepatocellular Carcinomas

 Dong Kyu Kim  ;  Joon Ho Kwon  ;  Jong Yun Won  ;  Kichang Han  ;  Gyoung Min Kim  ;  Man-Deuk Kim  ;  Do Yun Lee 
 Cardiovascular and Interventional Radiology, Vol.42(2) : 220-229, 2019 
Journal Title
 Cardiovascular and Interventional Radiology 
Issue Date
Ablation volume ; Hepatocelluar carcinoma ; Local tumor recurrence ; Percutaneous cryoablation
PURPOSE: To calculate the ablation volume of percutaneous cryoablation (PCA) with a two-cryo-probe technique for small hepatocellular carcinomas (HCCs) and to assess risk factors for local tumor recurrence (LTR). MATERIALS AND METHODS: Between January 2013 and June 2017, 96 patients (mean age, 60.7 years; range, 37-83 years) with 106 small HCCs were retrospectively analyzed. The ablation volume, technical success, LTR rates, and complications were evaluated. Ablation volume was measured after the first freezing and immediately after completing PCA twice via computed tomography imaging. Prognostic factors associated with LTR were analyzed. RESULTS: Technical success was achieved in all patients. The mean final ablation volume was 19.1 ± 4.8 cm3, which was significantly higher than the first freezing ablation volume (14.7 ± 4.3 cm3, p < 0.001). During the median follow-up period of 16.7 months (range, 5-52 months), LTR-free survival rates based on Kaplan-Meier analyses at 6 months, 1 year, and 2 years were 87.7%, 84.0%, and 80.2%, respectively. Only one major complication of post-procedural arterial bleeding occurred. A final ablation volume/tumor volume < 10 was a significant risk factor for LTR (p = 0.044). CONCLUSIONS: A ratio of final ablation volume to tumor volume < 10 was a significant prognostic factor for LTR. Therefore, the measurement and prediction of the final ablation volume are important to reduce LTR.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Joon Ho(권준호) ORCID logo https://orcid.org/0000-0002-6178-7252
Kim, Gyoung Min(김경민) ORCID logo https://orcid.org/0000-0001-6768-4396
Kim, Dong Kyu(김동규) ORCID logo https://orcid.org/0000-0001-7322-2550
Kim, Man Deuk(김만득) ORCID logo https://orcid.org/0000-0002-3575-5847
Won, Jong Yun(원종윤) ORCID logo https://orcid.org/0000-0002-8237-5628
Lee, Do Yun(이도연)
Han, Ki Chang(한기창) ORCID logo https://orcid.org/0000-0002-9701-9757
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.