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Use of F-18-sodium fluoride bone PET for disability evaluation in ankle trauma: a pilot study

DC FieldValueLanguage
dc.contributor.author김성준-
dc.contributor.author박중현-
dc.contributor.author박진영-
dc.contributor.author전태주-
dc.date.accessioned2018-10-22T13:18:46Z-
dc.date.available2018-10-22T13:18:46Z-
dc.date.issued2018-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/163744-
dc.description.abstractBACKGROUND: There are no objective and accurate rating tools for permanent impairment of traumatized ankles. The purpose of this study is to assess the role of 18F-Sodium fluoride (18F-NaF) positron emission tomography-computed tomography (PET/CT) bone scans in evaluating patients with limited ankle range of motion (ROM) after trauma. METHODS: 18F-NaF PET/CT was performed in 121 patients (75 men, 46 women; mean age: 45.8) who had ROM < 70% of normal after trauma affecting ankles. Metabolic target volume (MTV), the sum of voxels with standardized uptake value (SUV) > 2.5 was automatically obtained from the 3D volume that included the ankle joint. The maximum & mean SUV (SUVmax & SUVmean), and the total lesion activity (TLA) were measured. RESULTS: The median period from injury to performing 18F-NaF PET/CT was 290 days. The causes of injury were as follows: fracture (N = 95), Achilles tendon rupture (N = 12), and ligament injury (N = 12). Hot uptake in the ankle was seen in 113 of 121 patients. The fracture group had higher SUVmax, SUVmean, and TLA values than the non-fracture group. More limited ROM correlated with higher hot-uptake parameters (SUVmax, SUVmean, TLA). In subgroup analysis, the same correlations were present in the fracture, but not in the non-fracture group. CONCLUSIONS: 18F-NaF PET/CT can provide considerable information in impairment evaluations of limited ankle ROM, particularly in fracture around the ankle. Thus, 18F-NaF bone PET/CT may provide an additional option as an objective imaging tool in disability assessment after ankle injury.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfBMC Medical Imaging-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleUse of F-18-sodium fluoride bone PET for disability evaluation in ankle trauma: a pilot study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Radiology-
dc.contributor.googleauthorTae Joo Jeon-
dc.contributor.googleauthorSungjun Kim-
dc.contributor.googleauthorJinyoung Park-
dc.contributor.googleauthorJung Hyun Park-
dc.contributor.googleauthorEugene Y. Roh-
dc.identifier.doi10.1186/s12880-018-0277-1-
dc.contributor.localIdA00585-
dc.contributor.localIdA01682-
dc.contributor.localIdA04941-
dc.contributor.localIdA03557-
dc.relation.journalcodeJ03475-
dc.identifier.eissn1471-2342-
dc.identifier.pmid30236078-
dc.subject.keywordAnkle injuries-
dc.subject.keywordDisability evaluation-
dc.subject.keywordPET-CT-
dc.subject.keywordPositron emission tomography-
dc.subject.keywordRange of motion-
dc.contributor.alternativeNameKim, Sung Jun-
dc.contributor.alternativeNamePark, Jung Hyun-
dc.contributor.alternativeNamePark, Jinyoung-
dc.contributor.alternativeNameJeon, Tae Joo-
dc.contributor.affiliatedAuthorKim, Sung Jun-
dc.contributor.affiliatedAuthorPark, Jung Hyun-
dc.contributor.affiliatedAuthorPark, Jinyoung-
dc.contributor.affiliatedAuthorJeon, Tae Joo-
dc.citation.volume18-
dc.citation.startPage34-
dc.identifier.bibliographicCitationBMC Medical Imaging, Vol.18 : 34, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

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