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Direct Control of Stem Cell Behavior Using Biomaterials and Genetic Factors

DC FieldValueLanguage
dc.contributor.author김현옥-
dc.contributor.author박주현-
dc.contributor.author성학준-
dc.contributor.author이경미-
dc.contributor.author이진우-
dc.contributor.author윤정기-
dc.date.accessioned2018-10-11T08:58:04Z-
dc.date.available2018-10-11T08:58:04Z-
dc.date.issued2018-
dc.identifier.issn1687-966X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/163512-
dc.description.abstractStem cells have recently emerged as an important candidate for cell therapy. However, some major limitations still exist such as a small quantity of cell supply, senescence, and insufficient differentiation efficiency. Therefore, there is an unmet need to control stem cell behavior for better clinical performance. Since native microenvironment factors including stem cell niche, genetic factors, and growth factors direct stem cell fate cooperatively, user-specified in vitro settings are required to understand the regulatory roles and effects of each factor, thereby applying the factors for improved cell therapy. Among others, various types of biomaterials and transfection method have been employed as key tools for development of the in vitro settings. This review focuses on the current strategies to improve stemness maintenance, direct differentiation, and reprogramming using biomaterials and genetic factors without any aids from additional biochemicals and growth factors.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherHindawi-
dc.relation.isPartOfStem Cells International-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleDirect Control of Stem Cell Behavior Using Biomaterials and Genetic Factors-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Laboratory Medicine-
dc.contributor.googleauthorJeong-Kee Yoon-
dc.contributor.googleauthorMi-Lan Kang-
dc.contributor.googleauthorJoo Hyun Park-
dc.contributor.googleauthorKyoung-Mi Lee-
dc.contributor.googleauthorYoung Min Shin-
dc.contributor.googleauthorJin Woo Lee-
dc.contributor.googleauthorHyun Ok Kim-
dc.contributor.googleauthorHak-Joon Sung-
dc.identifier.doi10.1155/2018/8642989-
dc.contributor.localIdA01122-
dc.contributor.localIdA01668-
dc.contributor.localIdA01958-
dc.contributor.localIdA04619-
dc.contributor.localIdA03230-
dc.relation.journalcodeJ02685-
dc.identifier.eissn1687-9678-
dc.identifier.pmid29861745-
dc.contributor.alternativeNameKim, Hyun Ok-
dc.contributor.alternativeNamePark, Joo Hyun-
dc.contributor.alternativeNameSung, Hak-Joon-
dc.contributor.alternativeNameLee, Kyoung Mi-
dc.contributor.alternativeNameLee, Jin Woo-
dc.contributor.affiliatedAuthorKim, Hyun Ok-
dc.contributor.affiliatedAuthorPark, Joo Hyun-
dc.contributor.affiliatedAuthorSung, Hak-Joon-
dc.contributor.affiliatedAuthorLee, Kyoung Mi-
dc.contributor.affiliatedAuthorLee, Jin Woo-
dc.citation.volume2018-
dc.citation.startPage8642989-
dc.identifier.bibliographicCitationStem Cells International, Vol.2018 : 8642989, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers

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