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Comparison Between a Manual Squamous Cell Carcinoma Antigen Assay and an Automated Assay in a Clinical Setting

Authors
 Saejin Lee  ;  Juwon Kim  ;  Young Uh  ;  Hyon-Suk Kim  ;  Jong-Han Lee 
Citation
 LABORATORY MEDICINE, Vol.49(3) : 254-258, 2018 
Journal Title
 LABORATORY MEDICINE 
ISSN
 0007-5027 
Issue Date
2018
Abstract
Objective: To compare a manual squamous cell carcinoma antigen (SCCA) assay and an automated SCCA assay in a clinical setting. Methods: We included, in this study, a total of 158 specimens that had been tested using the manual SCCA assay. The CanAg SCC EIA assay and the Elecsys SCC were compared for their clinical settings. Results: Within-run and between-day coefficients of variation (CVs, %) were lower than 3%. Comparison of the manual and automated SCCA assays yielded good correlation. The correlation coefficient (R2) between the CanAg SCC EIA and Elecsys SCC assay results was 0.989 (P <.001) and the overall concordance rate was 94.3%. Conclusions: We report that the Elecsys SCC automated SCCA assay yielded performance comparable to that of the manual SCCA assay: the automated assay reduced the number of manual steps and test turnaround time.
Full Text
https://academic.oup.com/labmed/article-abstract/49/3/254/4939304?redirectedFrom=fulltext
DOI
10.1093/labmed/lmy003
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyon Suk(김현숙) ORCID logo https://orcid.org/0000-0001-5662-7740
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163200
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