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High sensitive detection of copper II ions using D-penicillamine-coated gold nanorods based on localized surface plasmon resonance

Authors
 Yoochan Hong  ;  Seongjae Jo  ;  Joohyung Park  ;  Jinsung Park  ;  Jaemoon Yang 
Citation
 NANOTECHNOLOGY, Vol.29(21) : 215501, 2018 
Journal Title
NANOTECHNOLOGY
ISSN
 0957-4484 
Issue Date
2018
Abstract
In this paper, we describe the development of a nanoplasmonic biosensor based on the localized surface plasmon resonance (LSPR) effect that enables a sensitive and selective recognition of copper II ions. First, we fabricated the nanoplasmonics as LSPR substrates using gold nanorods (GNR) and the nano-adsorption method. The LSPR sensitivity of the nanoplasmonics was evaluated using various solvents with different refractive indexes. Subsequently, D-penicillamine (DPA)-a chelating agent of copper II ions-was conjugated to the surface of the GNR. The limit of detection (LOD) for the DPA-conjugated nanoplasmonics was 100 pM. Furthermore, selectivity tests were conducted using various divalent cations, and sensitivity tests were conducted on the nanoplasmonics under blood-like environments. Finally, the developed nanoplasmonic biosensor based on GNR shows great potential for the effective recognition of copper II ions, even in human blood conditions.
Full Text
http://iopscience.iop.org/article/10.1088/1361-6528/aab4c4/meta
DOI
10.1088/1361-6528/aab4c4
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Yang, Jae Moon(양재문) ORCID logo https://orcid.org/0000-0001-7365-0395
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/162642
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