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Prevalence, sleep characteristics, and comorbidities in a population at high risk for obstructive sleep apnea: A nationwide questionnaire study in South Korea

 Jun-Sang Sunwoo  ;  Young Hwangbo  ;  Won-Joo Kim  ;  Min Kyung Chu  ;  Chang-Ho Yun  ;  Kwang Ik Yang 
 PLOS ONE, Vol.13(2) : e0193549, 2018 
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Adult ; Aged ; Comorbidity ; Female ; Humans ; Male ; Middle Aged ; Prevalence ; Republic of Korea/*epidemiology ; Risk ; Obstructive/*epidemiology Sleep Apnea ; *Surveys and Questionnaires
OBJECTIVE: To determine the prevalence, sleep characteristics, and comorbidities associated with a high risk for obstructive sleep apnea (OSA) in the Korean adult population. METHODS: We analyzed data from 2,740 subjects who responded to a nationwide questionnaire survey of sleep characteristics. Those who qualified under two or more symptom categories of the Berlin questionnaire were defined as "at high risk for OSA". We investigated their socio-demographic information, sleep habits, and medical and psychiatric comorbidities. Logistic regression analyses were performed to identify factors and consequences significantly associated with a high risk for OSA. RESULTS: The prevalence of a high risk for OSA was 15.8% (95% confidence interval [CI] 14.5-17.2%). Multiple logistic regression analysis showed that old age (>/= 70 years, odds ratio [OR] 2.68) and body mass index >/= 25 kg/m2 (OR 10.75) were significantly related with a high risk for OSA, whereas regular physical activity (OR 0.70) had a protective effect. Subjective sleep characteristics associated with a high risk for OSA were perceived insufficient sleep (OR 1.49), excessive daytime sleepiness (OR 1.88), and insomnia (OR 3.70). In addition, hypertension (OR 5.83), diabetes mellitus (OR 2.54), hyperlipidemia (OR 2.85), and anxiety (OR 1.63) were comorbid conditions independently associated with a high risk for OSA. CONCLUSIONS: This is the first study to demonstrate the prevalence of a high risk for OSA in a nationwide representative sample of the Korean adult population. These findings elucidate the epidemiology and clinical characteristics of those at high risk for OSA.
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1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Won Joo(김원주) ORCID logo https://orcid.org/0000-0002-5850-010X
Chu, Min Kyung(주민경) ORCID logo https://orcid.org/0000-0001-6221-1346
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