0 27

Cited 0 times in

Effect of diquafosol three per cent ophthalmic solution on tear film and corneal aberrations after cataract surgery

Authors
 Hun Lee  ;  Sang Myung Kim  ;  Seonghee Choi  ;  Kyoung Yul Seo  ;  Eung Kweon Kim  ;  Tae‐im Kim 
Citation
 Clinical & Experimental Optometry, Vol.100(6) : 590-594, 2017 
Journal Title
 Clinical & Experimental Optometry 
Issue Date
2017
MeSH
Aberrometry ; Administration, Ophthalmic ; Aged ; Corneal Wavefront Aberration/physiopathology* ; Dry Eye Syndromes/physiopathology ; Dry Eye Syndromes/prevention & control* ; Female ; Humans ; Lens Implantation, Intraocular* ; Male ; Middle Aged ; Ophthalmic Solutions ; Perioperative Care ; Phacoemulsification* ; Polyphosphates/administration & dosage* ; Purinergic P2Y Receptor Agonists/administration & dosage* ; Retrospective Studies ; Tears/physiology* ; Uracil Nucleotides/administration & dosage*
Keywords
OSDI ; cataract surgery ; corneal aberrations ; diquafosol ; tear film
Abstract
BACKGROUND: The aim was to evaluate the effect of diquafosol on tear film parameters and corneal aberrations after cataract surgery. METHODS: This retrospective, comparative, observational case series included patients who underwent cataract surgery with or without peri-operative use of diquafosol three per cent ophthalmic solution. Patients in group I (31 eyes) were treated with diquafosol three per cent ophthalmic solution six times a day from one week before surgery to three months after surgery. Patients in group II (33 eyes) underwent cataract surgery without being administered diquafosol. Tear film break-up time (BUT), the ocular surface disease index (OSDI), the Oxford Scheme score, Schirmer's test I and corneal aberrations were determined before and at one and three months post-surgery. RESULTS: In group I, the BUT, OSDI and Oxford Scheme score showed significant improvement at one and three months post-surgery (p = 0.002 for BUT at one month and three months, p = 0.023 and p = 0.049 for OSDI at one month and three months and p = 0.001 and p = 0.026 for Oxford Scheme at one month and three months), compared to baseline. In group II, the BUT, OSDI and Oxford Scheme score did not show any significant improvement during the follow-up period. In both groups, Schirmer's test I significantly decreased at three months post-surgery (p = 0.011 for group I and p = 0.034 for group II), compared to baseline. There were significant differences in the BUT and OSDI between the groups at three months post-surgery (p = 0.037 for BUT and p = 0.011 for OSDI). Regarding the corneal aberration, there were no significant differences between the groups at three months post-surgery. CONCLUSION: Peri-operative application of diquafosol three per cent ophthalmic solution may prevent dry eye-related ocular surface changes accompanied by improvement of ocular symptom. No definite changes in corneal aberrations were noted.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/161373
DOI
10.1111/cxo.12521
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실)
Yonsei Authors
김응권(Kim, Eung Kweon) ; 김태임(Kim, Tae Im) ; 서경률(Seo, Kyuong Yul)
사서에게 알리기
  feedback
Full Text
https://onlinelibrary.wiley.com/doi/abs/10.1111/cxo.12521
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse