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Effect of diquafosol three per cent ophthalmic solution on tear film and corneal aberrations after cataract surgery

DC FieldValueLanguage
dc.contributor.author김응권-
dc.contributor.author김태임-
dc.contributor.author서경률-
dc.date.accessioned2018-07-20T08:43:04Z-
dc.date.available2018-07-20T08:43:04Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161373-
dc.description.abstractBACKGROUND: The aim was to evaluate the effect of diquafosol on tear film parameters and corneal aberrations after cataract surgery. METHODS: This retrospective, comparative, observational case series included patients who underwent cataract surgery with or without peri-operative use of diquafosol three per cent ophthalmic solution. Patients in group I (31 eyes) were treated with diquafosol three per cent ophthalmic solution six times a day from one week before surgery to three months after surgery. Patients in group II (33 eyes) underwent cataract surgery without being administered diquafosol. Tear film break-up time (BUT), the ocular surface disease index (OSDI), the Oxford Scheme score, Schirmer's test I and corneal aberrations were determined before and at one and three months post-surgery. RESULTS: In group I, the BUT, OSDI and Oxford Scheme score showed significant improvement at one and three months post-surgery (p = 0.002 for BUT at one month and three months, p = 0.023 and p = 0.049 for OSDI at one month and three months and p = 0.001 and p = 0.026 for Oxford Scheme at one month and three months), compared to baseline. In group II, the BUT, OSDI and Oxford Scheme score did not show any significant improvement during the follow-up period. In both groups, Schirmer's test I significantly decreased at three months post-surgery (p = 0.011 for group I and p = 0.034 for group II), compared to baseline. There were significant differences in the BUT and OSDI between the groups at three months post-surgery (p = 0.037 for BUT and p = 0.011 for OSDI). Regarding the corneal aberration, there were no significant differences between the groups at three months post-surgery. CONCLUSION: Peri-operative application of diquafosol three per cent ophthalmic solution may prevent dry eye-related ocular surface changes accompanied by improvement of ocular symptom. No definite changes in corneal aberrations were noted.-
dc.description.statementOfResponsibilityrestriction-
dc.languageAustralia-
dc.publisher1444-0938-
dc.relation.isPartOfClinical & Experimental Optometry-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAberrometry-
dc.subject.MESHAdministration, Ophthalmic-
dc.subject.MESHAged-
dc.subject.MESHCorneal Wavefront Aberration/physiopathology*-
dc.subject.MESHDry Eye Syndromes/physiopathology-
dc.subject.MESHDry Eye Syndromes/prevention & control*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLens Implantation, Intraocular*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOphthalmic Solutions-
dc.subject.MESHPerioperative Care-
dc.subject.MESHPhacoemulsification*-
dc.subject.MESHPolyphosphates/administration & dosage*-
dc.subject.MESHPurinergic P2Y Receptor Agonists/administration & dosage*-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTears/physiology*-
dc.subject.MESHUracil Nucleotides/administration & dosage*-
dc.titleEffect of diquafosol three per cent ophthalmic solution on tear film and corneal aberrations after cataract surgery-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Ophthalmology-
dc.contributor.googleauthorHun Lee-
dc.contributor.googleauthorSang Myung Kim-
dc.contributor.googleauthorSeonghee Choi-
dc.contributor.googleauthorKyoung Yul Seo-
dc.contributor.googleauthorEung Kweon Kim-
dc.contributor.googleauthorTae‐im Kim-
dc.identifier.doi10.1111/cxo.12521-
dc.contributor.localIdA00831-
dc.contributor.localIdA01080-
dc.contributor.localIdA01870-
dc.relation.journalcodeJ03331-
dc.identifier.eissn0816-4622-
dc.identifier.pmid28222481-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/abs/10.1111/cxo.12521-
dc.subject.keywordOSDI-
dc.subject.keywordcataract surgery-
dc.subject.keywordcorneal aberrations-
dc.subject.keyworddiquafosol-
dc.subject.keywordtear film-
dc.contributor.alternativeNameKim, Eung Kweon-
dc.contributor.alternativeNameKim, Tae Im-
dc.contributor.alternativeNameSeo, Kyuong Yul-
dc.contributor.affiliatedAuthorKim, Eung Kweon-
dc.contributor.affiliatedAuthorKim, Tae Im-
dc.contributor.affiliatedAuthorSeo, Kyuong Yul-
dc.citation.volume100-
dc.citation.number6-
dc.citation.startPage590-
dc.citation.endPage594-
dc.identifier.bibliographicCitationClinical & Experimental Optometry, Vol.100(6) : 590-594, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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