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Stroke risk among adult patients with third, fourth or sixth cranial nerve palsy: a Nationwide Cohort Study

DC FieldValueLanguage
dc.contributor.author김성수-
dc.contributor.author이택준-
dc.contributor.author임형택-
dc.contributor.author최윤성-
dc.contributor.author한진우-
dc.date.accessioned2018-07-20T08:39:15Z-
dc.date.available2018-07-20T08:39:15Z-
dc.date.issued2017-
dc.identifier.issn1755-375X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161345-
dc.description.abstractPURPOSE: This study sought to determine whether isolated third, fourth and sixth cranial nerve palsies (NPs) are associated with increased short- and long-term risk of a subsequent stroke. METHODS: This was a nationwide retrospective propensity score-matched cohort study. A cohort of patients with NP (n = 466) and a randomly selected, propensity-matched control cohort (n = 2281) were extracted from the Korean national insurance claim database. Subjects were tracked for 5 years total, subdivided into periods of 0-1 years, 1-3 years and 3-5 years. We assessed the risk of stroke using hazard ratios (HRs) and confidence intervals (CIs) after adjustments using Cox regression at different time intervals. RESULTS: The median follow-up was 3.1 years. Stroke developed in 18.9% of the NP cohort and 7.5% of the control cohort. Stroke risk after NP was highest in the first year [14.7 per 100 person-year at 0-1 years (HR = 6.6), 3.1 per 100 person-year at 1-3 years (HR = 1.6) and 4.3 per 100 person-year at 3-5 years (HR = 2.8)]. Each type of NP was also associated with stroke risk: within 0-1 years, stroke risk was increased in third (HR = 7.6), fourth (HR = 6.0) and sixth (HR = 5. 84) NPs. In the 3- to 5-year period, risk was increased in sixth (HR = 4.7) and fourth (HR = 3.3) NPs, but not third (HR = 0.6) NPs. CONCLUSION: Patients in the NP cohort were more likely to have a stroke than those in the matched control cohort; the increased risk was both time- and cranial nerve-dependent.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherBlackwell Munksgaard-
dc.relation.isPartOfACTA OPHTHALMOLOGICA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAbducens Nerve Diseases/complications*-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOculomotor Nerve Diseases/complications*-
dc.subject.MESHPropensity Score*-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment*-
dc.subject.MESHRisk Factors-
dc.subject.MESHStroke/epidemiology*-
dc.subject.MESHStroke/etiology-
dc.subject.MESHTime Factors-
dc.subject.MESHTrochlear Nerve Diseases/complications*-
dc.titleStroke risk among adult patients with third, fourth or sixth cranial nerve palsy: a Nationwide Cohort Study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Ophthalmology-
dc.contributor.googleauthorTyler Hyungtaek Rim-
dc.contributor.googleauthorJinu Han-
dc.contributor.googleauthorYoon Seong Choi-
dc.contributor.googleauthorTaekjune Lee-
dc.contributor.googleauthorSung Soo Kim-
dc.identifier.doi10.1111/aos.13488-
dc.contributor.localIdA00571-
dc.contributor.localIdA04790-
dc.contributor.localIdA03419-
dc.contributor.localIdA04137-
dc.contributor.localIdA04329-
dc.relation.journalcodeJ00025-
dc.identifier.eissn1755-3768-
dc.identifier.pmid28772000-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/abs/10.1111/aos.13488-
dc.subject.keywordcranial nerve palsy-
dc.subject.keywordfourth nerve palsy-
dc.subject.keywordsixth nerve palsy-
dc.subject.keywordstroke-
dc.subject.keywordthird nerve palsy-
dc.contributor.alternativeNameKim, Sung Soo-
dc.contributor.alternativeNameLee, Taek June-
dc.contributor.alternativeNameRim, Tyler Hyungtaek-
dc.contributor.alternativeNameChoi, Yoon Seong-
dc.contributor.alternativeNameHan, Jin U-
dc.contributor.affiliatedAuthorKim, Sung Soo-
dc.contributor.affiliatedAuthorLee, Taek June-
dc.contributor.affiliatedAuthorRim, Tyler Hyungtaek-
dc.contributor.affiliatedAuthorChoi, Yoon Seong-
dc.contributor.affiliatedAuthorHan, Jin U-
dc.citation.volume95-
dc.citation.number7-
dc.citation.startPagee656-
dc.citation.endPagee661-
dc.identifier.bibliographicCitationACTA OPHTHALMOLOGICA, Vol.95(7) : e656-e661, 2017-
dc.identifier.rimsid61264-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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