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Validation of the modified 4-tiered categorization system through comparison with the 5-tiered categorization system of the 2015 American Thyroid Association guidelines for classifying small thyroid nodules on ultrasound

Authors
 Ji Hye Lee  ;  Kyunghwa Han  ;  Eun‐Kyung Kim  ;  Hee Jung Moon  ;  Jung Hyun Yoon  ;  Vivian Y. Park  ;  Jin Young Kwak 
Citation
 Head & Neck, Vol.39(11) : 2208-2215, 2017 
Journal Title
 Head & Neck 
ISSN
 1043-3074 
Issue Date
2017
Keywords
biopsy ; fine-needle aspiration ; practice guideline ; thyroid nodule ; ultrasonography
Abstract
BACKGROUND: The purpose of this study was to validate the modified 4-tiered categorization system and to compare stratification of malignancy risk in small thyroid nodules with the 2015 American Thyroid Association (ATA) management guidelines. METHODS: From January 2015 to December 2015, 737 thyroid nodules measured ≥ 1 cm and <2 cm were included in this study. Each nodule was assigned a category with the ultrasonographic patterns described by the 2015 ATA guidelines. RESULTS: On univariate analysis, there was no difference of malignancy risk between low suspicion and very low suspicion nodules (P = .584). Therefore, we suggested a modified 4-tiered categorization, which combines very low suspicion and low suspicion nodules into the "revised low suspicion" category. Specificity, positive predictive value (PPV) and accuracy were higher with the modified 4-tiered categorization system (P < .001 for all). CONCLUSION: The modified 4-tiered categorization system allows more efficient management with better diagnostic performance than the 2015 ATA categorization system in small thyroid nodules.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/161147
DOI
10.1002/hed.24888
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)
Yonsei Authors
곽진영(Kwak, Jin Young) ; 김은경(Kim, Eun-Kyung) ; 문희정(Moon, Hee Jung) ; 박영진(Park, Vivian Youngjean) ; 윤정현(Yoon, Jung Hyun)
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Full Text
https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.24888
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