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Strategies for using nanoprobes to perceive and treat cancer activity: a review

Authors
 Byunghoon Kang,#1 Aastha Kukreja,#1 Daesub Song,corresponding author3 Yong-Min Huh,corresponding author2 and Seungjoo Haamcorresponding author1 
Citation
 Journal of Biological Engineering, Vol.11 : 13, 2017 
Journal Title
 Journal of Biological Engineering 
Issue Date
2017
Keywords
Cancer activity ; Nanoparticles ; Stimuli responsive
Abstract
Nanomedicine has seen a significant increase in research on stimuli-responsive activatable nanoprobes for tumor-specific delivery and diagnosis. The tumor microenvironment has particular characteristics that can be exploited to implement therapeutic strategies based on disparities between normal tissues and tumor tissues, including differences in pH, oxygenation, enzymatic expression, gene activation/inactivation, and vasculature. The nanocarriers of activatable nanoparticles maintain their structure while circulating in the body and, upon reaching the tumor site, are altered by unique tumoral stimuli, leading to the release of a drug or other agent. This review demonstrates the latest achievements in the use of internal stimuli-responsive, activatable nanoparticles with respect to unique design strategies and applications.
Files in This Item:
T201703849.pdf Download
DOI
10.1186/s13036-016-0044-1
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
허용민(Huh, Yong Min) ORCID logo https://orcid.org/0000-0002-9831-4475
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161001
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