Cited 26 times in
Poor long-term outcomes in stroke patients with asymptomatic coronary artery disease in heart CT
DC Field | Value | Language |
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dc.contributor.author | 김경섭 | - |
dc.contributor.author | 김영대 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 백장현 | - |
dc.contributor.author | 송동범 | - |
dc.contributor.author | 유준상 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 허지회 | - |
dc.date.accessioned | 2018-07-20T08:00:07Z | - |
dc.date.available | 2018-07-20T08:00:07Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160746 | - |
dc.description.abstract | BACKGROUND AND AIMS: Although stroke patients have a high risk of ischemic heart disease, little information is available on the risk of coronary events in stroke patients with asymptomatic coronary artery disease (CAD). We investigated the long-term vascular outcomes in stroke patients with asymptomatic CAD diagnosed with multi-detector coronary computed tomography (MDCT). METHODS: This study was a retrospective analysis using a prospective cohort of ischemic stroke patients. We included consecutive stroke patients without history or symptoms of CAD who underwent MDCT. We investigated the long-term risk of major adverse cardiovascular events (MACE: cardiovascular mortality, ischemic stroke, myocardial infarction, unstable angina, and urgent coronary revascularization) and composite of MACE/all-cause mortality/elective coronary revascularization. We further investigated the value of MDCT for MACE prediction. RESULTS: Among the 1893 included patients, 1349 (71.3%) patients had some degree of CAD and 654 patients (34.5%) had significant (≥50%) CAD. At follow-up (median, 4.4 years), MACE occurred in 230 patients (12.2%). Event rates of MACE increased with the increasing extent of CAD. After adjustment for age, sex, and risk factors, the hazard ratios for MACE in mild CAD, 1-VD, 2-VD, and 3-VD or left main coronary disease were 1.28 (95% confidence interval [CI]: 0.88-1.87), 1.39 (95% CI: 0.90-2.16), 2.22 (95% CI: 1.39-3.55), and 2.91 (95% CI: 1.82-4.65), respectively (no CAD as a reference). Diagnosis of asymptomatic CAD significantly improved the prediction of MACE. CONCLUSIONS: Asymptomatic CAD detected on MDCT was associated with increased risks of vascular events or deaths in acute stroke patients. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | ATHEROSCLEROSIS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Poor long-term outcomes in stroke patients with asymptomatic coronary artery disease in heart CT | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Neurology | - |
dc.contributor.googleauthor | Joonsang Yoo | - |
dc.contributor.googleauthor | Dongbeom Song | - |
dc.contributor.googleauthor | Jang-Hyun Baek | - |
dc.contributor.googleauthor | Kyoungsub Kim | - |
dc.contributor.googleauthor | Jinkwon Kim | - |
dc.contributor.googleauthor | Tae-Jin Song | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Young Dae Kim | - |
dc.contributor.googleauthor | Hyo Suk Nam | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2017.07.029 | - |
dc.contributor.localId | A05088 | - |
dc.contributor.localId | A00702 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A01834 | - |
dc.contributor.localId | A02017 | - |
dc.contributor.localId | A02513 | - |
dc.contributor.localId | A03312 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A04369 | - |
dc.relation.journalcode | J00260 | - |
dc.identifier.eissn | 1879-1484 | - |
dc.identifier.pmid | 28825975 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0021915017312169 | - |
dc.subject.keyword | Coronary artery disease | - |
dc.subject.keyword | Ischemic stroke | - |
dc.subject.keyword | Major adverse cardiac event | - |
dc.subject.keyword | Mortality | - |
dc.subject.keyword | Multidetector computerized tomography | - |
dc.contributor.alternativeName | Kim, Kyoung Sub | - |
dc.contributor.alternativeName | Kim, Young Dae | - |
dc.contributor.alternativeName | Nam, Hyo Suk | - |
dc.contributor.alternativeName | Baek, Jang Hyun | - |
dc.contributor.alternativeName | Song, Dong Beom | - |
dc.contributor.alternativeName | Yoo, Joon Sang | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.alternativeName | Heo, Ji Hoe | - |
dc.contributor.affiliatedAuthor | Kim, Kyoung Sub | - |
dc.contributor.affiliatedAuthor | Kim, Young Dae | - |
dc.contributor.affiliatedAuthor | Nam, Hyo Suk | - |
dc.contributor.affiliatedAuthor | Baek, Jang Hyun | - |
dc.contributor.affiliatedAuthor | Song, Dong Beom | - |
dc.contributor.affiliatedAuthor | Yoo, Joon Sang | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Heo, Ji Hoe | - |
dc.citation.volume | 265 | - |
dc.citation.startPage | 7 | - |
dc.citation.endPage | 13 | - |
dc.identifier.bibliographicCitation | ATHEROSCLEROSIS, Vol.265 : 7-13, 2017 | - |
dc.identifier.rimsid | 60632 | - |
dc.type.rims | ART | - |
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