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T1 bright appendix sign to exclude acute appendicitis in pregnant women

Authors
 Ilah Shin  ;  Chansik An  ;  Joon Seok Lim  ;  Myeong-Jin Kim  ;  Yong Eun Chung 
Citation
 EUROPEAN RADIOLOGY, Vol.27(8) : 3310-3316, 2017 
Journal Title
EUROPEAN RADIOLOGY
ISSN
 0938-7994 
Issue Date
2017
MeSH
Acute Disease ; Adult ; Appendicitis/diagnostic imaging* ; Appendix/diagnostic imaging ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Predictive Value of Tests ; Pregnancy ; Pregnancy Complications/diagnostic imaging* ; Retrospective Studies ; Sensitivity and Specificity
Keywords
Abdomen, acute ; Abdominal pain ; Appendicitis ; Magnetic resonance imaging ; Pregnancy
Abstract
OBJECTIVE: To evaluate the diagnostic value of the T1 bright appendix sign for the diagnosis of acute appendicitis in pregnant women.

MATERIAL AND METHODS: This retrospective study included 125 pregnant women with suspected appendicitis who underwent magnetic resonance (MR) imaging. The T1 bright appendix sign was defined as a high intensity signal filling more than half length of the appendix on T1-weighted imaging. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the T1 bright appendix sign for normal appendix identification were calculated in all patients and in those with borderline-sized appendices (6-7 mm).

RESULTS: The T1 bright appendix sign was seen in 51% of patients with normal appendices, but only in 4.5% of patients with acute appendicitis. The overall sensitivity, specificity, PPV, and NPV of the T1 bright appendix sign for normal appendix diagnosis were 44.9%, 95.5%, 97.6%, and 30.0%, respectively. All four patients with borderline sized appendix with appendicitis showed negative T1 bright appendix sign.

CONCLUSION: The T1 bright appendix sign is a specific finding for the diagnosis of a normal appendix in pregnant women with suspected acute appendicitis.

KEY POINTS: • Magnetic resonance imaging is increasingly used in emergency settings. • Acute appendicitis is the most common cause of acute abdomen. • Magnetic resonance imaging is widely used in pregnant population. • T1 bright appendix sign can be a specific sign representing normal appendix.
Full Text
https://link.springer.com/article/10.1007%2Fs00330-016-4727-2
DOI
10.1007/s00330-016-4727-2
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
An, Chansik(안찬식) ORCID logo https://orcid.org/0000-0002-0484-6658
Lim, Joon Seok(임준석) ORCID logo https://orcid.org/0000-0002-0334-5042
Chung, Yong Eun(정용은) ORCID logo https://orcid.org/0000-0003-0811-9578
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160494
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