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Cited 4 times in

Functional connectivity of the circadian clock and neural substrates of sleep-wake disturbance in delirium

DC FieldValueLanguage
dc.contributor.author경성현-
dc.contributor.author김재진-
dc.contributor.author양규현-
dc.contributor.author이우석-
dc.contributor.author정태섭-
dc.date.accessioned2018-07-20T07:38:32Z-
dc.date.available2018-07-20T07:38:32Z-
dc.date.issued2017-
dc.identifier.issn0165-1781-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160368-
dc.description.abstractA possible mechanism of disrupted circadian rhythms in delirium was identified using resting-state functional connectivity. Thirty-four delirious patients and 38 non-delirious controls were scanned for resting-state functional MRI. Seed-based connectivity of the suprachiasmatic nucleus was compared between the groups. In delirious patients functional connectivity from the circadian clock was increased to the dorsal anterior cingulate cortex and decreased to the posterior cingulate cortex, parahippocampal gyrus, cerebellum, and thalamus. A dysregulation of the default mode network and mental coordination processing areas by the circadian clock may be the underlying pathophysiology of sleep-wake cycle disturbance and symptom fluctuation in delirium.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier/North-Holland Biomedical Press-
dc.relation.isPartOfPSYCHIATRY RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHCerebral Cortex/diagnostic imaging*-
dc.subject.MESHCerebral Cortex/physiopathology-
dc.subject.MESHCircadian Clocks/physiology*-
dc.subject.MESHCircadian Rhythm/physiology-
dc.subject.MESHDelirium/diagnostic imaging*-
dc.subject.MESHDelirium/physiopathology-
dc.subject.MESHDelirium/psychology-
dc.subject.MESHFemale-
dc.subject.MESHGyrus Cinguli/diagnostic imaging-
dc.subject.MESHGyrus Cinguli/physiopathology-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging/methods-
dc.subject.MESHMale-
dc.subject.MESHNerve Net/diagnostic imaging*-
dc.subject.MESHNerve Net/physiopathology-
dc.subject.MESHSleep Disorders, Circadian Rhythm/diagnostic imaging*-
dc.subject.MESHSleep Disorders, Circadian Rhythm/physiopathology-
dc.subject.MESHThalamus/diagnostic imaging*-
dc.subject.MESHThalamus/physiopathology-
dc.titleFunctional connectivity of the circadian clock and neural substrates of sleep-wake disturbance in delirium-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Life Science-
dc.contributor.googleauthorSunghyon Kyeong-
dc.contributor.googleauthorSoo-Hee Choi-
dc.contributor.googleauthorJung Eun Shin-
dc.contributor.googleauthorWoo Suk Lee-
dc.contributor.googleauthorKyu Hyun Yang-
dc.contributor.googleauthorTae-Sub Chung-
dc.contributor.googleauthorJae-Jin Kim-
dc.identifier.doi10.1016/j.pscychresns.2017.03.017-
dc.contributor.localIdA04506-
dc.contributor.localIdA00870-
dc.contributor.localIdA02282-
dc.contributor.localIdA02992-
dc.contributor.localIdA03751-
dc.relation.journalcodeJ02571-
dc.identifier.eissn1872-7123-
dc.identifier.pmid28390292-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0925492716303389-
dc.subject.keywordDelirium-
dc.subject.keywordFunctional connectivity-
dc.subject.keywordSuprachiasmatic nucleus-
dc.contributor.alternativeNameKyeong, Sung Hyon-
dc.contributor.alternativeNameKim, Jae Jin-
dc.contributor.alternativeNameYang, Kyu Hyun-
dc.contributor.alternativeNameLee, Woo Suk-
dc.contributor.alternativeNameChung, Tae Sub-
dc.contributor.affiliatedAuthorKyeong, Sung Hyon-
dc.contributor.affiliatedAuthorKim, Jae Jin-
dc.contributor.affiliatedAuthorYang, Kyu Hyun-
dc.contributor.affiliatedAuthorLee, Woo Suk-
dc.contributor.affiliatedAuthorChung, Tae Sub-
dc.citation.volume264-
dc.citation.startPage10-
dc.citation.endPage12-
dc.identifier.bibliographicCitationPSYCHIATRY RESEARCH, Vol.264 : 10-12, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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