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The long-term oncological and functional outcomes of transoral robotic surgery in patients with hypopharyngeal cancer

Authors
 Young Min Park  ;  Chan Min Jung  ;  Dongchul Cha  ;  Se-Heon Kim 
Citation
 ORAL ONCOLOGY, Vol.71 : 138-143, 2017 
Journal Title
 ORAL ONCOLOGY 
ISSN
 1368-8375 
Issue Date
2017
MeSH
Aged ; Aged, 80 and over ; Humans ; Hypopharyngeal Neoplasms/physiopathology ; Hypopharyngeal Neoplasms/surgery* ; Male ; Middle Aged ; Mouth ; Prospective Studies ; Robotic Surgical Procedures/methods* ; Survival Analysis ; Treatment Outcome
Keywords
Hypopharyngeal cancer ; Organ preservation ; Transoral robotic surgery
Abstract
OBJECTIVE: We conducted a prospective clinical trial of transoral robotic surgery in patients with hypopharyngeal cancer and herein report the long-term oncological and functional outcomes. MATERIALS AND METHODS: Between April 2008 and March 2014, 45 patients diagnosed with hypopharyngeal cancer participated in this prospective study. RESULTS: All patients were male with a mean age of 66.7years. The median follow-up period was 60months. Patients were classified using the staging system of the American Joint Commission on Cancer, as follows: Stage I, 7.9%; Stage II, 5.3%; Stage III, 15.8%; Stage IV, 71.1. Of all 38 patients, 17 (44.7%) were alive with no evidence of disease at the last follow-up. Seven patients (18.4%) died of TNM-related disease and fourteen (36.8%) from other causes. The 5-year disease-specific survival rate of stage I and II patients was 100.0%, and that of stage III and IV patients was 74.0%. The 5-year disease-free survival rate was 100.0% for stage I and II patients and 68.6% for stage III and IV patients. CONCLUSIONS: Patients who underwent TORS exhibited oncological outcomes comparable to those of conventional therapies and rapid functional recovery with low surgical morbidity. TORS and simultaneous neck dissection, with or without adjuvant therapy, may be effective alternatives to existing treatment methods.
Full Text
https://www.sciencedirect.com/science/article/pii/S1368837517301677
DOI
10.1016/j.oraloncology.2017.06.016
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Se Heon(김세헌)
Jung, Chan Min(정찬민) ORCID logo https://orcid.org/0000-0002-1445-2564
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160316
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