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Esophageal involvement of pemphigus vulgaris associated with upper gastrointestinal bleeding

 Sooyun Chang  ;  Soo Jung Park  ;  Sun Wook Kim  ;  Moo-Nyun Jin  ;  Jung-Hee Lee  ;  Hyun Ju Kim  ;  Sung Pil Hong  ;  Tae Il Kim 
 CLINICAL ENDOSCOPY, Vol.47(5) : 452-454, 2014 
Journal Title
Issue Date
Pemphigus ; Esophageal involvement ; Upper gastrointestinal bleeding
Esophageal involvement of pemphigus vulgaris is rare, and when present, the most common presenting symptoms reported in the medical literature are odynophagia and dysphagia. Here, we present two cases of pemphigus vulgaris presenting with upper gastrointestinal hemorrhage because of esophageal involvement of the disease. In case 1, a 41-year-old female patient with a prior diagnosis of pemphigus vulgaris presented with hematemesis. Esophagogastroduodenoscopy showed diffuse mucosal exfoliation and oozing bleeding of the oropharynx and esophagus. The patient recovered after the administration of high-dose corticosteroids and immunosuppressants. In case 2, a 30-year-old female patient with known pemphigus vulgaris also presented with hematemesis, showing similar endoscopic findings to the first case. She also responded to the same treatment. Esophageal involvement of pemphigus vulgaris responds to high-dose corticosteroids and immunosuppressants. Thus, in patients with pemphigus vulgaris with signs or symptoms of upper gastrointestinal bleeding, an early endoscopy for the evaluation of esophageal involvement is beneficial.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers
Yonsei Authors
Kim, Sun Wook(김선욱)
Kim, Hyun Ju(김현주)
Park, Soo Jung(박수정)
Lee, Jung Hee(이정희)
Chang, Soo Yun(장수연)
Jin, Moo Nyun(진무년) ORCID logo https://orcid.org/0000-0001-5482-4441
Hong, Sung Pil(홍성필)
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