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Differential Prognostic Value of Coronary Computed Tomography Angiography in Relation to Exercise Electrocardiography in Asymptomatic Subjects

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dc.contributor.author성지민-
dc.contributor.author심지영-
dc.contributor.author이상은-
dc.contributor.author장혁재-
dc.contributor.author정남식-
dc.contributor.author조익성-
dc.contributor.author조인정-
dc.contributor.author최병욱-
dc.contributor.author홍그루-
dc.date.accessioned2018-03-26T17:04:02Z-
dc.date.available2018-03-26T17:04:02Z-
dc.date.issued2015-
dc.identifier.issn1975-4612-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/157136-
dc.description.abstractBACKGROUND: To explore the prognostic performance of coronary computed tomography angiography (CCTA) and exercise electrocardiography (XECG) in asymptomatic subjects. METHODS: We retrospectively enrolled 812 (59 ± 9 years, 60.8% male) asymptomatic subjects who underwent CCTA and XECG concurrently from 2003 through 2009. Subjects were followed-up for major adverse cardiac events (MACE) including cardiac death, nonfatal myocardial infarction, unstable angina, and revascularization after 90 days from index CCTA. RESULTS: The prevalence of occult coronary artery disease (CAD) detected by CCTA was 17.5% and 120 subjects (14.8%) had positive XECG. During a mean follow-up of 37 ± 16 months, nine subjects experienced MACE. In multivariable Cox-regression analysis, only the presence of CAD by CCTA independently predicted future MACE (p = 0.002). Moreover, CAD by CCTA improved the predictive value when added to a clinical risk factor model using the likelihood ratio test (p < 0.001). Notably, the prognostic value of CCTA persisted in the moderate-to-high-risk group as classified by the Duke treadmill score (p = 0.040), but not in the low-risk group (p = 0.991). CONCLUSION: CCTA provides incremental prognostic benefit over and above XECG in an asymptomatic population, especially for those in a moderate-to-high-risk group as classified by the Duke treadmill score. Risk stratification using XECG may prove valuable for identifying asymptomatic subjects who can benefit from CCTA.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean, English-
dc.publisherKorean Society of Echocardiography-
dc.relation.isPartOfJournal of Cardiovascular Ultrasound-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleDifferential Prognostic Value of Coronary Computed Tomography Angiography in Relation to Exercise Electrocardiography in Asymptomatic Subjects-
dc.typeArticle-
dc.contributor.collegeResearch Institutes-
dc.contributor.departmentYonsei Cardiovascular Research Institute-
dc.contributor.googleauthorSang-Eun Lee-
dc.contributor.googleauthorIksung Cho-
dc.contributor.googleauthorGeu-Ru Hong-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.contributor.googleauthorJi Min Sung-
dc.contributor.googleauthorIn-Jeong Cho-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorByoung Wook Choi-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.4250/jcu.2015.23.4.244-
dc.contributor.localIdA01955-
dc.contributor.localIdA02213-
dc.contributor.localIdA02827-
dc.contributor.localIdA03490-
dc.contributor.localIdA03585-
dc.contributor.localIdA03888-
dc.contributor.localIdA03892-
dc.contributor.localIdA04059-
dc.contributor.localIdA04386-
dc.relation.journalcodeJ01298-
dc.identifier.eissn2005-9655-
dc.identifier.pmid26755933-
dc.subject.keywordAsymptomatic population-
dc.subject.keywordCoronary artery disease-
dc.subject.keywordCoronary computed tomography angiography-
dc.subject.keywordExercise electrocardiography-
dc.contributor.alternativeNameSung, Ji Min-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameLee, Sang Eun-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameCho, Ik Sung-
dc.contributor.alternativeNameCho, In Jeong-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.affiliatedAuthorSung, Ji Min-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorLee, Sang Eun-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorCho, Ik Sung-
dc.contributor.affiliatedAuthorCho, In Jeong-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.citation.volume23-
dc.citation.number4-
dc.citation.startPage244-
dc.citation.endPage252-
dc.identifier.bibliographicCitationJournal of Cardiovascular Ultrasound, Vol.23(4) : 244-252, 2015-
dc.identifier.rimsid41699-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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