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The effect of consumption of ethanol on subfoveal choroidal thickness in acute phase

Authors
 Hae Min Kang  ;  Young Jae Woo  ;  Hyoung Jun Koh  ;  Christopher Seungkyu Lee  ;  Sung Chul Lee 
Citation
 BRITISH JOURNAL OF OPHTHALMOLOGY, Vol.100(3) : 383-388, 2016 
Journal Title
 BRITISH JOURNAL OF OPHTHALMOLOGY 
ISSN
 0007-1161 
Issue Date
2016
Abstract
BACKGROUND/AIMS: To investigate the acute effect of ethanol consumption on subfoveal choroidal thickness. METHODS: This prospective interventional study included the right eyes of 30 healthy subjects (30 eyes). Ethanol (1.0 g/kg) was administered orally on the first visit. A matching volume of water was administered orally on the second visit. Oral administration of ethanol and water was performed at 14:00, and choroidal thickness was measured every 30 min until 16:00. Change of choroidal thickness after oral administration of ethanol and water was the main outcome measure. RESULTS: At baseline, choroidal mean subfoveal thickness was 299.0±73.4 µm (range, 186.5-472.5 µm) before ethanol consumption and 297.1±71.1 µm (range, 187.0-470.5 µm) before water consumption. After consumption of ethanol, mean subfoveal choroidal thickness increased during the first 60 min and then decreased during the next 60 min, which was a significant change over time (p<0.001). After consumption of water, there was no significant change in mean subfoveal choroidal thickness over time (p=0.310). Comparison of changes in the mean subfoveal choroidal thickness during 120 min showed significant difference between ethanol and water consumption (p<0.001). CONCLUSIONS: The results of current study show that consumption of ethanol significantly affected the choroidal thickness. Mean subfoveal choroidal thickness increased during the first 60 min and then decreased during the next 120 min after ethanol consumption.
Full Text
http://bjo.bmj.com/content/100/3/383
DOI
10.1136/bjophthalmol-2015-306969
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Woo, Young Jae(우영재)
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/155807
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