0 108

Cited 6 times in

Assessment of myocardial delayed enhancement with cardiac computed tomography in cardiomyopathies: a prospective comparison with delayed enhancement cardiac magnetic resonance imaging

 Hye-Jeong Lee  ;  Dong Jin Im  ;  Jong-Chan Youn  ;  Suyon Chang  ;  Young Joo Suh  ;  Yoo Jin Hong  ;  Young Jin Kim  ;  Jin Hur  ;  Byoung Wook Choi 
 International Journal of Cardiovascular Imaging, Vol.33(4) : 577-584, 2017 
Journal Title
 International Journal of Cardiovascular Imaging 
Issue Date
Adult ; Aged ; Aged, 80 and over ; Cardiomyopathies/diagnostic imaging* ; Cardiomyopathies/etiology ; Cardiomyopathies/pathology ; Contrast Media/administration & dosage ; Feasibility Studies ; Female ; Humans ; Iopamidol/administration & dosage ; Magnetic Resonance Imaging/methods* ; Male ; Middle Aged ; Myocardium/pathology* ; Observer Variation ; Organometallic Compounds/administration & dosage ; Predictive Value of Tests ; Prospective Studies ; Reproducibility of Results ; Tomography, X-Ray Computed/methods* ; Young Adult
Cardiac computed tomography ; Cardiac magnetic resonance imaging ; Cardiomyopathy ; Myocardial delayed enhancement ; Myocardial fibrosis
To evaluate the feasibility of cardiac CT for the evaluation of myocardial delayed enhancement (MDE) in the assessment of patients with cardiomyopathy, compared to cardiac MRI. A total of 37 patients (mean age 54.9 ± 15.7 years, 24 men) who underwent cardiac MRI to evaluate cardiomyopathy were enrolled. Dual-energy ECG-gated cardiac CT was acquired 12 min after contrast injection. Two observers evaluated cardiac MRI and cardiac CT at different kV settings (100, 120 and 140 kV) independently for MDE pattern-classification (patchy, transmural, subendocardial, epicardial and mesocardial), differentiation between ischemic and non-ischemic cardiomyopathy and MDE quantification (percentage MDE). Kappa statics and the intraclass correlation coefficient were used for statistical analysis. Among different kV settings, 100-kV CT showed excellent agreements compared to cardiac MRI for MDE detection (κ = 0.886 and 0.873, respectively), MDE pattern-classification (κ = 0.888 and 0.881, respectively) and differentiation between ischemic and non-ischemic cardiomyopathy (κ = 1.000 and 0.893, respectively) for both Observer 1 and Observer 2. The Bland-Altman plot between MRI and 100-kV CT for the percentage MDE showed a very small bias (-0.15%) with 95% limits of agreement of -7.02 and 6.72. Cardiac CT using 100 kV might be an alternative method to cardiac MRI in the assessment of cardiomyopathy, particularly in patients with contraindications to cardiac MRI.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김영진(Kim, Young Jin) ORCID logo https://orcid.org/0000-0002-6235-6550
서영주(Suh, Young Joo) ORCID logo https://orcid.org/0000-0002-2078-5832
윤종찬(Youn, Jong Chan)
이혜정(Lee, Hye Jeong) ORCID logo https://orcid.org/0000-0003-4349-9174
임동진(Im, Dong Jin) ORCID logo https://orcid.org/0000-0001-8139-5646
장수연(Chang, Su Yon)
최병욱(Choi, Byoung Wook) ORCID logo https://orcid.org/0000-0002-8873-5444
허진(Hur, Jin) ORCID logo https://orcid.org/0000-0002-8651-6571
홍유진(Hong, Yoo Jin) ORCID logo https://orcid.org/0000-0002-7276-0944
RIS (EndNote)
XLS (Excel)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.