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Language Development and Brain Magnetic Resonance Imaging Characteristics in Preschool Children With Cerebral Palsy

DC FieldValueLanguage
dc.contributor.author박은숙-
dc.contributor.author최윤성-
dc.contributor.author최자영-
dc.date.accessioned2017-11-02T08:15:00Z-
dc.date.available2017-11-02T08:15:00Z-
dc.date.issued2017-
dc.identifier.issn1092-4388-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154251-
dc.description.abstractPURPOSE: The purpose of this study was to investigate characteristics of language development in relation to brain magnetic resonance imaging (MRI) characteristics and the other contributing factors to language development in children with cerebral palsy (CP). METHOD: The study included 172 children with CP who underwent brain MRI and language assessments between 3 and 7 years of age. The MRI characteristics were categorized as normal, malformation, periventricular white matter lesion (PVWL), deep gray matter lesion, focal infarct, cortical/subcortical lesion, and others. Neurodevelopmental outcomes such as ambulatory status, manual ability, cognitive function, and accompanying impairments were assessed. RESULTS: Both receptive and expressive language development quotients (DQs) were significantly related to PVWL or deep gray matter lesion severity. In multivariable analysis, only cognitive function was significantly related to receptive language development, whereas ambulatory status and cognitive function were significantly associated with expressive language development. More than one third of the children had a language developmental discrepancy between receptive and expressive DQs. Children with cortical/subcortical lesions were at high risk for this discrepancy. CONCLUSIONS: Cognitive function is a key factor for both receptive and expressive language development. In children with PVWL or deep gray matter lesion, lesion severity seems to be useful to predict language development.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherAmerican Speech-Language-Hearing Association-
dc.relation.isPartOfJournal of Speech, Language, and Hearing Research-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBrain/diagnostic imaging*-
dc.subject.MESHCerebral Palsy/diagnostic imaging*-
dc.subject.MESHCerebral Palsy/psychology*-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHFemale-
dc.subject.MESHGray Matter/diagnostic imaging-
dc.subject.MESHHumans-
dc.subject.MESHLanguage Development*-
dc.subject.MESHLanguage Tests-
dc.subject.MESHMagnetic Resonance Imaging*-
dc.subject.MESHMale-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHRegression Analysis-
dc.subject.MESHSeverity of Illness Index-
dc.titleLanguage Development and Brain Magnetic Resonance Imaging Characteristics in Preschool Children With Cerebral Palsy-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Rehabilitation Medicine-
dc.contributor.googleauthorJa Young Choi-
dc.contributor.googleauthorYoon Seong Choi-
dc.contributor.googleauthorEun Sook Park-
dc.identifier.doi10.1044/2016_JSLHR-L-16-0281-
dc.contributor.localIdA04137-
dc.contributor.localIdA04170-
dc.contributor.localIdA01611-
dc.relation.journalcodeJ03087-
dc.relation.journalsince1997-
dc.identifier.pmid28492849-
dc.identifier.urlhttps://jslhr.pubs.asha.org/article.aspx?articleid=2627036-
dc.contributor.alternativeNamePark, Eun Sook-
dc.contributor.alternativeNameChoi, Yoon Seong-
dc.contributor.alternativeNameChoi, Ja Young-
dc.contributor.affiliatedAuthorChoi, Yoon Seong-
dc.contributor.affiliatedAuthorChoi, Ja Young-
dc.contributor.affiliatedAuthorPark, Eun Sook-
dc.citation.titleJournal of Speech, Language, and Hearing Research-
dc.citation.volume60-
dc.citation.number5-
dc.citation.startPage1330-
dc.citation.endPage1338-
dc.identifier.bibliographicCitationJournal of Speech, Language, and Hearing Research, Vol.60(5) : 1330-1338, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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