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The association of pulse pressure with metabolic syndrome in Korean elderly: A nationwide population-based stud

Authors
 Yu-Jin Kwon  ;  Tae-Ha Chung  ;  Jae-Yong Shim  ;  Yong-Jae Lee 
Citation
 DIABETES RESEARCH AND CLINICAL PRACTICE, Vol.123(1) : 75-81, 2017 
Journal Title
 DIABETES RESEARCH AND CLINICAL PRACTICE 
ISSN
 0168-8227 
Issue Date
2017
MeSH
Aged ; Aged, 80 and over ; Blood Pressure* ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Male ; Metabolic Syndrome/epidemiology* ; Metabolic Syndrome/physiopathology ; Middle Aged ; Nutrition Surveys ; Prevalence ; Republic of Korea/epidemiology
Keywords
Arterial stiffness ; Inflammation ; Insulin resistance ; Metabolic syndrome ; Pulse pressure
Abstract
AIMS: Metabolic syndrome (MetS) is one of the most important issues in elderly people because of its association with ensuing cardiovascular disease (CVD). The components of MetS play a key role in the pathogenesis of arterial thickness and stiffness. Pulse pressure (PP), an easily accessible parameter in a basic health evaluation, has been documented as a marker of arterial stiffness and widespread atherosclerosis. The aim of our study was to assess the association between PP and MetS in Korean elderly people. METHODS: A nationwide cross-sectional study was conducted to examine the relationship between PP and MetS among 6187 participants (2687 men and 3500 women) aged 60years older Korean people using the Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) for MetS were calculated across PP quartiles using multiple logistic regression analyses. RESULTS: There was a positive relationship between PP and MetS in a dose-response manner. The prevalence of MetS significantly increased with increasing PP quartile in both men and women (p<0.001). Compared with the lowest PP quartile group, the ORs (95% CIs) for MetS of the highest PP quartile was 2.60 (1.91-3.52) for men and 1.97 (1.48-2.59) for women after adjusting for age, cigarette smoking, alcohol intake, regular exercise and mean arterial blood pressure. These associations remained valid after additionally adjusting for hypertension and diabetes medications. CONCLUSION: We found a positive relationship between PP and MetS among Korean elderly men and women.
Full Text
http://www.sciencedirect.com/science/article/pii/S0168822716317260
DOI
10.1016/j.diabres.2016.11.027
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers
Yonsei Authors
Kwon, Yu-Jin(권유진) ORCID logo https://orcid.org/0000-0002-9021-3856
Shim, Jae Yong(심재용) ORCID logo https://orcid.org/0000-0002-9561-9230
Lee, Yong Jae(이용제) ORCID logo https://orcid.org/0000-0002-6697-476X
Chung, Tae-Ha(정태하) ORCID logo https://orcid.org/0000-0001-5873-3352
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/154140
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