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Evaluation of the Association Between Retinal Vein Occlusion and the Risk of Atrial Fibrillation Development: A 12-Year, Retrospective Nationwide Cohort Study

Authors
 Tyler Hyungtaek Rim  ;  Jaewon Oh  ;  Christopher Seungkyu Lee  ;  Sung Chul Lee  ;  Seok-Min Kang  ;  Sung Soo Kim 
Citation
 SCIENTIFIC REPORTS, Vol.6 : 34708, 2016 
Journal Title
 SCIENTIFIC REPORTS 
Issue Date
2016
Abstract
We aimed to evaluate the risk of atrial fibrillation (AF) development following retinal vein occlusion (RVO). We performed a nationwide propensity score-matched cohort study by retrospectively reviewing a database from the Korean National Health Insurance Service, comprising approximately 1 million random subjects. RVO and AF were diagnosed based on the Korean Classification of Disease codes. The RVO group was composed of patients with an initial diagnosis of RVO made between 2003 and 2007 (n?=?1,801), excluding those who were diagnosed in 2002. The comparison group was composed of randomly selected patients (5 for each patient with RVO, n?=?8,930) who were matched to the RVO group according to sociodemographic factors and the year of enrollment. Each sampled patient was tracked until 2013. The predictive value of RVO for AF was analyzed using Cox regression analysis with a hazard ratio (HR) and confidence interval (CI). AF developed in 6.5% of patients in the RVO group and 4.0% of those in the comparison group (p?<?0.001). RVO was associated with a greater risk of AF development after adjusting for possible confounders (HR, 1.35; 95% CI, 1.09-1.67). An association between RVO and subsequent AF development was found after adjusting for possible confounding factors.
Files in This Item:
T201605611.pdf Download
DOI
10.1038/srep34708
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seok Min(강석민) ORCID logo https://orcid.org/0000-0001-9856-9227
Kim, Sung Soo(김성수) ORCID logo https://orcid.org/0000-0002-0574-7993
Oh, Jae Won(오재원) ORCID logo https://orcid.org/0000-0002-4585-1488
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
Rim, Tyler Hyungtaek(임형택)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/152893
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