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Imaging Features of Infratentorial Desmoplastic Infantile and Non-Infantile Tumors

Other Titles
 천막하부 결합조직형성의 영아성 그리고 비영아성 종양의 영상 소견 
 Hyun Gi Kim  ;  Seung-Koo Lee  ;  Hyun Joo Shin  ;  Se Hoon Kim  ;  Myung-Joon Kim  ;  Mi-Jung Lee 
 Journal of the Korean Society of Radiology, Vol.75(1) : 49-56, 2016 
Journal Title
Journal of the Korean Society of Radiology(대한영상의학회지)
Issue Date
Desmoplastic Cerebral Astrocytoma of Infancy ; Magnetic Resonance Imaging ; Pediatrics ; Brain Tumor
Purpose : To describe imaging features of infratentorial desmoplastic infantile or non-infantile tumors (DIT/DNIT).

Materials and Methods : Four cases with infratentorial DIT/DNIT from our hospital and 5 cases from literature review were analyzed. Clinical data and MR imaging features were evaluated including location, size, shape, margin, composition, dural attachment, perilesional edema, and metastasis or multiplicity.

Results : The mean age was 9.2 years (range, 1?18 years). Most of the patients presented with headache or vomiting (4/9, 44.4%) and had no underlying disease (8/9, 88.9%). The major pathologic subtype was astrocytoma (6/9, 66.7%). On MR, majority of the tumors involved cerebellum and/or spinal cord (8/9, 88.9%) and the mean size of the tumors was 4.2 cm (range, 3.2?5 cm). The tumors were mainly solid (4/9, 44.4%) or mixed (4/9, 44.4%) in composition with lobulated shape (7/9, 77.8%) and well-defined margin (7/9, 77.8%). Two cases (2/7, 28.6%) showed dural attachment and all the cases had no or minimal perilesional edema (100%). Metastasis or multiplicity was frequently seen in 44.4% (4/9).

Conclusion : Infratentorial DIT/DNIT occurred in relatively older children and the major tumor type was astrocytoma. They also had atypical imaging features showing mainly solid or mixed in composition with frequent metastasis or multiplicity.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myung Joon(김명준) ORCID logo https://orcid.org/0000-0002-4608-0275
Kim, Se Hoon(김세훈) ORCID logo https://orcid.org/0000-0001-7516-7372
Kim, Hyun Gi(김현지)
Shin, Hyun Joo(신현주) ORCID logo https://orcid.org/0000-0002-7462-2609
Lee, Mi-Jung(이미정) ORCID logo https://orcid.org/0000-0003-3244-9171
Lee, Seung Koo(이승구) ORCID logo https://orcid.org/0000-0001-5646-4072
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