Cited 15 times in
Prognostic value of urine dipstick proteinuria on mortality after acute ischemic stroke
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김영대 | - |
dc.contributor.author | 남정모 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 백장현 | - |
dc.contributor.author | 송동범 | - |
dc.contributor.author | 유준상 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 허지회 | - |
dc.date.accessioned | 2017-10-26T07:24:52Z | - |
dc.date.available | 2017-10-26T07:24:52Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151999 | - |
dc.description.abstract | BACKGROUND AND AIMS: Proteinuria is a marker of kidney disease and a strong risk factor for cardiovascular diseases including stroke. This study was aimed at investigating the prognostic value of proteinuria measured by urine dipstick in patients with acute ischemic stroke. METHODS: This post-hoc analysis of a prospective cohort study included 3404 consecutive patients who had been admitted for acute ischemic stroke between November 2005 and June 2013. Proteinuria was defined as a trace or more of protein on a urine dipstick test routinely performed at admission. Date and cause of death until December 31, 2013 were collected. We investigated the association of proteinuria with all-cause mortality, cardiovascular mortality (defined as ICD-10 codes I00-I99), and non-cardiovascular mortality. RESULTS: Proteinuria was present in 12.8% of the 3404 patients. During the mean follow-up period of 3.56 ± 2.22 years, there were 681 cases of all-cause mortality (460 cardiovascular deaths and 221 non-cardiovascular deaths). Multivariate Cox regression analysis showed that the presence of proteinuria was an independent risk factor for all-cause mortality (adjusted hazard ratio [HR] 1.69, 95% confidence interval [CI] 1.40-2.04), cardiovascular mortality (adjusted HR 1.65, 95% CI 1.31-2.08), and non-cardiovascular mortality (adjusted HR 1.59, 95% CI 1.13-2.23). Adding proteinuria to the multivariate Cox models moderately improved the model performance for all-cause mortality (integrated area under curve [95% CI]: from 0.800 [0.784-0.816] to 0.803 [0.788-0.818], p = 0.026). CONCLUSIONS: Proteinuria, which was detected on a urine dipstick test, was a significant predictor of mortality after acute ischemic stroke. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | ATHEROSCLEROSIS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Area Under Curve | - |
dc.subject.MESH | Biomarkers/urine | - |
dc.subject.MESH | Brain Ischemia/mortality* | - |
dc.subject.MESH | Brain Ischemia/urine* | - |
dc.subject.MESH | Cardiovascular Diseases/complications | - |
dc.subject.MESH | Data Interpretation, Statistical | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Patient Admission | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Proteinuria/diagnosis* | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Stroke/mortality* | - |
dc.subject.MESH | Stroke/urine* | - |
dc.title | Prognostic value of urine dipstick proteinuria on mortality after acute ischemic stroke | - |
dc.type | Article | - |
dc.publisher.location | Ireland | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Neurology | - |
dc.contributor.googleauthor | Jinkwon Kim | - |
dc.contributor.googleauthor | Tae-Jin Song | - |
dc.contributor.googleauthor | Dongbeom Song | - |
dc.contributor.googleauthor | Joonsang Yoo | - |
dc.contributor.googleauthor | Jang-Hyun Baek | - |
dc.contributor.googleauthor | Chung Mo Nam | - |
dc.contributor.googleauthor | , Hye Sun Lee | - |
dc.contributor.googleauthor | Hyo Suk Nam | - |
dc.contributor.googleauthor | Young Dae Kim | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2016.08.030 | - |
dc.contributor.localId | A01264 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A01834 | - |
dc.contributor.localId | A02017 | - |
dc.contributor.localId | A02513 | - |
dc.contributor.localId | A03312 | - |
dc.contributor.localId | A04369 | - |
dc.contributor.localId | A00702 | - |
dc.relation.journalcode | J00260 | - |
dc.identifier.eissn | 1879-1484 | - |
dc.identifier.pmid | 27599365 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0021915016312916?via%3Dihub | - |
dc.subject.keyword | Chronic Kidney Disease | - |
dc.subject.keyword | Ischemic stroke | - |
dc.subject.keyword | Mortality | - |
dc.subject.keyword | Proteinuria | - |
dc.contributor.alternativeName | Kim, Young Dae | - |
dc.contributor.alternativeName | Nam, Jung Mo | - |
dc.contributor.alternativeName | Nam, Hyo Suk | - |
dc.contributor.alternativeName | Baek, Jang Hyun | - |
dc.contributor.alternativeName | Song, Dong Beom | - |
dc.contributor.alternativeName | Yoo, Joon Sang | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Heo, Ji Hoe | - |
dc.contributor.affiliatedAuthor | Nam, Jung Mo | - |
dc.contributor.affiliatedAuthor | Nam, Hyo Suk | - |
dc.contributor.affiliatedAuthor | Baek, Jang Hyun | - |
dc.contributor.affiliatedAuthor | Song, Dong Beom | - |
dc.contributor.affiliatedAuthor | Yoo, Joon Sang | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.contributor.affiliatedAuthor | Heo, Ji Hoe | - |
dc.contributor.affiliatedAuthor | Kim, Young Dae | - |
dc.citation.volume | 253 | - |
dc.citation.startPage | 118 | - |
dc.citation.endPage | 123 | - |
dc.identifier.bibliographicCitation | ATHEROSCLEROSIS, Vol.253 : 118-123, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 46321 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.