0 131

Cited 22 times in

Prediction of biochemical recurrence after radical prostatectomy with PI-RADS version 2 in prostate cancers: initial results

DC FieldValueLanguage
dc.contributor.author나군호-
dc.contributor.author조남훈-
dc.contributor.author최영득-
dc.contributor.author홍성준-
dc.contributor.author박성윤-
dc.contributor.author오영택-
dc.contributor.author정대철-
dc.date.accessioned2017-10-26T07:15:34Z-
dc.date.available2017-10-26T07:15:34Z-
dc.date.issued2016-
dc.identifier.issn0938-7994-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151807-
dc.description.abstractOBJECTIVES: To determine whether the Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) helps predict biochemical recurrence (BCR) after radical prostatectomy for prostate cancer (PCa). METHODS: We included 158 patients with PCa who underwent magnetic resonance imaging (MRI) and radical prostatectomy (RP). Clinical (prostate-specific antigen, greatest percentage of core, and percentage of positive core number), PI-RADSv2 score on MRI, and surgical parameters (Gleason score, extracapsular extension, seminal vesicle invasion, and tumour volume) were investigated. Univariate and multivariate analyses using Cox's proportional hazards model were performed to assess parameters predictive of BCR (two consecutive prostate specific antigens ≥0.2 ng/ml). Kaplan-Meier survival curves were analyzed. RESULTS: The rate of BCR was 13.3 % (21/158) after surgery (median follow-up, 25 months; range, 12-36). No subject with a PI-RADS score <4 had BCR. In univariate analysis, all parameters were significant for BCR (p?<?0.05), except seminal vesicle invasion (p?=?0.254). Meanwhile, PI-RADS score was the only independent parameter for BCR in multivariate analysis (p?<?0.05). Two-year, BCR-free survival post-RP was significantly lower for PI-RADS ≥4 (84.7-85.5 %) than for PI-RADS <4 (100 %; p?<?0.05). CONCLUSION: As a preoperative imaging tool, PI-RADSv2 may be useful to predict BCR after radical prostatectomy for PCa. POINTS: ? No subject with PI-RADS <4 had BCR after RP ? PI-RADSv2 was the only predictor of BCR in multivariate analysis ? Two-year, BCR-free survival following RP was lower for PI-RADS≥4 than for PI-RADS<4 ? Inter-rater agreement was good for PI-RADS ≥4 or not.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSpringer International-
dc.relation.isPartOfEuropean Radiology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMagnetic Resonance Imaging/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHNeoplasm Recurrence, Local*/metabolism-
dc.subject.MESHNeoplasm Recurrence, Local*/pathology-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHProstate-Specific Antigen/analysis*-
dc.subject.MESHProstatectomy/methods-
dc.subject.MESHProstatic Neoplasms/diagnostic imaging*-
dc.subject.MESHProstatic Neoplasms/metabolism-
dc.subject.MESHProstatic Neoplasms/pathology-
dc.subject.MESHRetrospective Studies-
dc.titlePrediction of biochemical recurrence after radical prostatectomy with PI-RADS version 2 in prostate cancers: initial results-
dc.typeArticle-
dc.publisher.locationGermany-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Urology-
dc.contributor.googleauthorSung Yoon Park-
dc.contributor.googleauthorYoung Taik Oh-
dc.contributor.googleauthorDae Chul Jung-
dc.contributor.googleauthorNam Hoon Cho-
dc.contributor.googleauthorYoung Deuk Choi-
dc.contributor.googleauthorKoon Ho Rha-
dc.contributor.googleauthorSung Joon Hong-
dc.identifier.doi10.1007/s00330-015-4077-5-
dc.contributor.localIdA03812-
dc.contributor.localIdA04111-
dc.contributor.localIdA04402-
dc.contributor.localIdA01509-
dc.contributor.localIdA02390-
dc.contributor.localIdA03592-
dc.contributor.localIdA01227-
dc.relation.journalcodeJ00851-
dc.identifier.pmid26560721-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00330-015-4077-5-
dc.subject.keywordBiochemical recurrence-
dc.subject.keywordMRI-
dc.subject.keywordPI-RADS-
dc.subject.keywordProstate cancer-
dc.subject.keywordRadical prostatectomy-
dc.contributor.alternativeNameRha, Koon Ho-
dc.contributor.alternativeNameCho, Nam Hoon-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.alternativeNameHong, Sung Joon-
dc.contributor.alternativeNamePark, Sung Yoon-
dc.contributor.alternativeNameOh, Young Taik-
dc.contributor.alternativeNameJung, Dae Chul-
dc.contributor.affiliatedAuthorCho, Nam Hoon-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.contributor.affiliatedAuthorHong, Sung Joon-
dc.contributor.affiliatedAuthorPark, Sung Yoon-
dc.contributor.affiliatedAuthorOh, Young Taik-
dc.contributor.affiliatedAuthorJung, Dae Chul-
dc.contributor.affiliatedAuthorRha, Koon Ho-
dc.citation.volume26-
dc.citation.number8-
dc.citation.startPage2502-
dc.citation.endPage2509-
dc.identifier.bibliographicCitationEuropean Radiology, Vol.26(8) : 2502-2509, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.