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The Role of Radiosurgery in the Management of Benign Head and Neck Tumors.

Authors
 Hun Ho Park  ;  Chang-Ki Hong  ;  Hyun Ho Jung  ;  Won Seok Chang  ;  Chang-Hoon Kim  ;  Won Sang Lee  ;  Sung Chul Lee  ;  Yong Gou Park  ;  Jong Hee Chang 
Citation
 World Neurosurgery, Vol.87 : 116-123, 2016 
Journal Title
 World Neurosurgery 
ISSN
 1878-8750 
Issue Date
2016
MeSH
Adenoma, Pleomorphic/surgery ; Adolescent ; Adult ; Aged ; Angiofibroma/surgery ; Child ; Confounding Factors (Epidemiology) ; Female ; Follow-Up Studies ; Head and Neck Neoplasms/complications ; Head and Neck Neoplasms/pathology* ; Head and Neck Neoplasms/physiopathology ; Head and Neck Neoplasms/surgery* ; Hemangioma/surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neurilemmoma/surgery ; Radiosurgery*/methods ; Retrospective Studies ; Treatment Outcome ; Tumor Burden/radiation effects*
Keywords
Benign tumors ; Extracranial extension ; Gamma knife radiosurgery ; Head and neck ; Stereotactic radiosurgery
Abstract
OBJECTIVE: Head and neck tumors are a heterogeneous group and often invade the skull base. Various radiation techniques can be used for these tumors when surgery is unavailable. This study investigated the indications for gamma knife radiosurgery (GKRS) in benign head and neck tumors. METHODS: Thirty-seven lesions in 35 patients were treated with GKRS for schwannoma, juvenile nasal angiofibroma, choroidal hemangioma, and pleomorphic adenoma. The median follow-up period was 43.0 months (range, 12.2-174.1 months). RESULTS: Tumor control was achieved in 35 of 37 lesions (94.6%) at last follow-up after GKRS. Thirty-four lesions (91.9%) decreased, 1 lesion (2.7%) remained stable, and 2 lesions (5.4%) increased in size. Clinically, 15 cases (40.5%) showed improvement, 17 cases (45.9%) were stable, 1 case (2.7%) experienced deterioration, and 4 cases (10.8%) developed new symptoms. Four of the 5 cases that exhibited deterioration or new symptoms improved. CONCLUSIONS: GKRS is a reasonable alternative to surgery that can effectively control tumor growth and preserve functions of the head and neck in primary, residual, or recurrent benign head and neck tumors.
Full Text
http://www.sciencedirect.com/science/article/pii/S187887501501654X
DOI
10.1016/j.wneu.2015.11.053
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chang Hoon(김창훈) ORCID logo https://orcid.org/0000-0003-1238-6396
Park, Yong Gou(박용구)
Park, Hun Ho(박현호) ORCID logo https://orcid.org/0000-0002-2526-9693
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Won Sang(이원상)
Chang, Won Seok(장원석) ORCID logo https://orcid.org/0000-0003-3145-4016
Chang, Jong Hee(장종희)
Jung, Hyun Ho(정현호)
Hong, Chang Ki(홍창기)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146577
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