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Evaluation of Underlying Lymphocytic Thyroiditis With Histogram Analysis Using Grayscale Ultrasound Images

DC FieldValueLanguage
dc.contributor.author곽진영-
dc.contributor.author김가람-
dc.contributor.author김은경-
dc.contributor.author문희정-
dc.contributor.author윤정현-
dc.contributor.author홍정화-
dc.date.accessioned2017-02-24T07:50:42Z-
dc.date.available2017-02-24T07:50:42Z-
dc.date.issued2016-
dc.identifier.issn0278-4297-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146536-
dc.description.abstractOBJECTIVES: The purpose of this study was to evaluate diagnostic performance of histogram analysis using grayscale ultrasound (US) images in the diagnosis of lymphocytic thyroiditis. METHODS: Three radiologists reviewed a total of 505 US images and classified the images according to the presence/existence of lymphocytic thyroiditis. After 2 months, each reviewer repeated the process with the same 505 images in a randomly mixed order. The intraobserver and interobserver variability was analyzed with a generalized κ value. Four histogram parameters (mean value, standard deviation, skewness, and kurtosis) were obtained, and an index was calculated from principal component analysis. Diagnostic performances were compared. RESULTS: Of 505 patients, 125 (24.8%) had lymphocytic thyroiditis, and 380 (75.2%) had normal thyroid parenchyma on pathologic analysis. The κ value for intraobserver variance ranged from -0.002 to 0.781, and the overall κ values for interobserver variance were 0.570 and 0.214 in the first and second tests, respectively. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for the 3 reviewers versus the principal component analysis index were 28.0% to 83.2%, 43.7% to 82.6%, 53.5% to 79.0%, 24.6% to 56.2%, and 75.2% to 88.9% versus 58.4%, 72.4%, 68.9%, 41.0%, and 84.1%. CONCLUSIONS: Histogram analysis of grayscale US images provided confirmable and quantitative information about lymphocytic thyroiditis and was comparable with performers' assessments in diagnostic performance.-
dc.description.statementOfResponsibilityrestriction-
dc.format.extent519~526-
dc.languageEnglish-
dc.publisherAmerican Institute of Ultrasound in Medicine-
dc.relation.isPartOfJournal of Ultrasound in Medicine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAlgorithms*-
dc.subject.MESHData Interpretation, Statistical*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImage Enhancement/methods-
dc.subject.MESHImage Interpretation, Computer-Assisted/methods*-
dc.subject.MESHMachine Learning*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHObserver Variation-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHThyroiditis, Autoimmune/diagnostic imaging*-
dc.subject.MESHUltrasonography/methods*-
dc.subject.MESHYoung Adult-
dc.titleEvaluation of Underlying Lymphocytic Thyroiditis With Histogram Analysis Using Grayscale Ultrasound Images-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Radiology-
dc.contributor.googleauthorGa Ram Kim-
dc.contributor.googleauthorEun-Kyung Kim-
dc.contributor.googleauthorSoo Jin Kim-
dc.contributor.googleauthorEun Ju Ha-
dc.contributor.googleauthorJaeheung Yoo-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorJung Hwa Hong-
dc.contributor.googleauthorJung Hyun Yoon-
dc.contributor.googleauthorHee Jung Moon-
dc.contributor.googleauthorJin Young Kwak-
dc.identifier.doi10.7863/ultra.15.04014-
dc.contributor.localIdA00182-
dc.contributor.localIdA00284-
dc.contributor.localIdA00801-
dc.contributor.localIdA01397-
dc.contributor.localIdA02595-
dc.contributor.localIdA04433-
dc.relation.journalcodeJ01920-
dc.identifier.pmid26887447-
dc.identifier.urlhttp://www.jultrasoundmed.org/content/35/3/519-
dc.subject.keywordhead and neck ultrasound-
dc.subject.keywordhistogram analysis-
dc.subject.keywordlymphocytic thyroiditis-
dc.subject.keywordthyroid gland-
dc.subject.keywordultrasound-
dc.contributor.alternativeNameKwak, Jin Young-
dc.contributor.alternativeNameKim, Ga Ram-
dc.contributor.alternativeNameKim, Eun Kyung-
dc.contributor.alternativeNameMoon, Heui Jeong-
dc.contributor.alternativeNameYoon, Jung Hyun-
dc.contributor.alternativeNameHong, Jung Hwa-
dc.contributor.affiliatedAuthorKwak, Jin Young-
dc.contributor.affiliatedAuthorKim, Ga Ram-
dc.contributor.affiliatedAuthorKim, Eun-Kyung-
dc.contributor.affiliatedAuthorMoon, Heui Jeong-
dc.contributor.affiliatedAuthorYoon, Jung Hyun-
dc.contributor.affiliatedAuthorHong, Jung Hwa-
dc.citation.volume35-
dc.citation.number3-
dc.citation.startPage519-
dc.citation.endPage526-
dc.identifier.bibliographicCitationJournal of Ultrasound in Medicine, Vol.35(3) : 519-526, 2016-
dc.date.modified2017-02-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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