Cited 13 times in
Short-term Follow-up US Leads to Higher False-positive Results Without Detection of Structural Recurrences in PTMC
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 곽진영 | - |
dc.contributor.author | 김은경 | - |
dc.contributor.author | 문희정 | - |
dc.contributor.author | 육지현 | - |
dc.contributor.author | 윤정현 | - |
dc.contributor.author | 이혜선 | - |
dc.date.accessioned | 2017-02-24T03:11:03Z | - |
dc.date.available | 2017-02-24T03:11:03Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146272 | - |
dc.description.abstract | To investigate the value of the annual follow-up neck ultrasonography (US) for postoperative surveillance in patients with papillary thyroid microcarcinoma (PTMC). This retrospective study has been approved by our institutional review board (IRB) with waiver for informed consent. A total of 375 patients diagnosed as PTMCs, who underwent total thyroidectomy with radioiodine remnant ablation were included, to identify the recurrence rate and the false-positive rate of annual ultrasound. The number, interval, and the results of follow-up US or fine needle aspiration were obtained from electronic medical records. Four (1.1%, 4/375) recurrences were found 3 years after the initial treatment, and only 1 patient (0.3%, 1/375) had a metastatic lymph node larger than 8 mm in the shortest diameter on US found 7.6 years after initial treatment with biochemical abnormalities. Cumulative risk of having at least 1 false-positive exam was 8.3% by the 8th US, and 8.1% by the 8-9 year follow-up. Cox multivariate regression showed shorter interval of follow-up US and presence of lymph node metastasis at initial surgery are independent predictors affecting the cumulative false-positive results (hazard ratio [HR], 0.60; 95% confidence interval [CI]: 0.49-0.73; P < 0.001 and HR, 2.19; 95% CI: 1.01-4.75; P = 0.048, respectively). Short-term follow-up US can result in higher cumulative false-positive results without detection of meaningful recurrences in patients with PTMCs who do not have biochemical abnormalities. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Ablation Techniques/methods | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Carcinoma, Papillary/diagnostic imaging* | - |
dc.subject.MESH | Carcinoma, Papillary/pathology | - |
dc.subject.MESH | Carcinoma, Papillary/surgery | - |
dc.subject.MESH | False Positive Reactions | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Iodine Radioisotopes/therapeutic use | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neck/diagnostic imaging* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Thyroid Neoplasms/diagnostic imaging* | - |
dc.subject.MESH | Thyroid Neoplasms/pathology | - |
dc.subject.MESH | Thyroid Neoplasms/surgery | - |
dc.subject.MESH | Thyroidectomy/methods | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Ultrasonography | - |
dc.title | Short-term Follow-up US Leads to Higher False-positive Results Without Detection of Structural Recurrences in PTMC | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Radiology | - |
dc.contributor.googleauthor | Jung Hyun Yoon | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Eun-Kyung Kim | - |
dc.contributor.googleauthor | Ji Hyun Youk | - |
dc.contributor.googleauthor | Hyun Gi Kim | - |
dc.contributor.googleauthor | Hee Jung Moon | - |
dc.contributor.googleauthor | Jin Young Kwak | - |
dc.identifier.doi | 10.1097/MD.0000000000002435 | - |
dc.contributor.localId | A00182 | - |
dc.contributor.localId | A00801 | - |
dc.contributor.localId | A01397 | - |
dc.contributor.localId | A02537 | - |
dc.contributor.localId | A02595 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J02214 | - |
dc.identifier.eissn | 1536-5964 | - |
dc.identifier.pmid | 26735548 | - |
dc.contributor.alternativeName | Kwak, Jin Young | - |
dc.contributor.alternativeName | Kim, Eun Kyung | - |
dc.contributor.alternativeName | Moon, Heui Jeong | - |
dc.contributor.alternativeName | Youk, Ji Hyun | - |
dc.contributor.alternativeName | Yoon, Jung Hyun | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.affiliatedAuthor | Kwak, Jin Young | - |
dc.contributor.affiliatedAuthor | Kim, Eun-Kyung | - |
dc.contributor.affiliatedAuthor | Moon, Heui Jeong | - |
dc.contributor.affiliatedAuthor | Youk, Ji Hyun | - |
dc.contributor.affiliatedAuthor | Yoon, Jung Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.citation.volume | 95 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 2435 | - |
dc.identifier.bibliographicCitation | MEDICINE, Vol.95(1) : 2435, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 51321 | - |
dc.type.rims | ART | - |
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