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Thyroid Imaging Reporting and Data System and Ultrasound Elastography: Diagnostic Accuracy as a Tool in Recommending Repeat Fine-Needle Aspiration for Solid Thyroid Nodules with Non-Diagnostic Fine-Needle Aspiration Cytology

Authors
 VIVIAN YOUNGJEAN PARK  ;  EUN-KYUNG KIM  ;  JIN YOUNG KWAK  ;  JUNG HYUN YOON  ;  MIN JUNG KIM  ;  HEE JUNG MOON 
Citation
 Ultrasound in Medicine and Biology, Vol.42(2) : 399-406, 2016 
Journal Title
 Ultrasound in Medicine and Biology 
ISSN
 0301-5629 
Issue Date
2016
MeSH
Adult ; Aged ; Elasticity Imaging Techniques/methods* ; Endoscopic Ultrasound-Guided Fine Needle Aspiration/methods* ; Female ; Humans ; Image Enhancement/methods ; Image Interpretation, Computer-Assisted/methods* ; Male ; Middle Aged ; Radiology Information Systems/organization & administration* ; Sensitivity and Specificity ; Thyroid Nodule/diagnosis*
Keywords
Elastography ; Fine-needle aspiration ; Non-diagnostic cytology ; Thyroid nodule ; Ultrasonography
Abstract
The Thyroid Imaging Reporting and Data System (TIRADS) has been found to be accurate in the stratification of malignancy risk, and elastography has been found to have a high negative predictive value in non-diagnostic thyroid nodules. Through assessment of 104 solid non-diagnostic thyroid nodules, this study investigated the role of both in recommending repeat ultrasonography-guided fine-needle aspiration for solid thyroid nodules with non-diagnostic cytology. All nodules were classified by TIRADS (categories 4a, 4b, 4c and 5), and elastography scores were assigned according to the Rago and Asteria criteria. The malignancy risks for TIRADS categories 4a, 4b, 4c and 5 were 12.5%, 25.0%, 25.8% and 16.7%, respectively. Elastography revealed the highest diagnostic performance for TIRADS category 4a, with a sensitivity, specificity, negative predictive value, positive predictive value and accuracy of 100%, 85.7%, 100%, 50% and 87.5% for the Asteria criteria. Observation may be considered for non-diagnostic solid nodules that have no other suspicious ultrasonographic features and are also benign on real-time strain elastography using the Asteria criteria.
Full Text
http://www.sciencedirect.com/science/article/pii/S0301562915006250
DOI
10.1016/j.ultrasmedbio.2015.10.011
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
곽진영(Kwak, Jin Young) ORCID logo https://orcid.org/0000-0002-6212-1495
김민정(Kim, Min Jung) ORCID logo https://orcid.org/0000-0003-4949-1237
김은경(Kim, Eun-Kyung) ORCID logo https://orcid.org/0000-0002-3368-5013
문희정(Moon, Hee Jung) ORCID logo https://orcid.org/0000-0002-5643-5885
박영진(Park, Vivian Youngjean) ORCID logo https://orcid.org/0000-0002-5135-4058
윤정현(Yoon, Jung Hyun) ORCID logo https://orcid.org/0000-0002-2100-3513
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146268
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