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위장관에 발생한 급성 이식편 대 숙주 질환의 MR 소견

Other Titles
 MR Findings of Acute Graft-versus-Host Disease Involving Gastrointestinal Tracts 
Authors
 정재준  ;  김명진  ;  양희철  ;  이종태  ;  유형식  ;  김주희 
Citation
 Journal of the Korean Radiologist Society (대한방사선의학회지), Vol.47(4) : 373-378, 2002 
Journal Title
 Journal of the Korean Radiologist Society (대한방사선의학회지) 
ISSN
 1738-2637 
Issue Date
2002
Keywords
Gastrointestinal tract ; MRMagnetic resonance (MR) ; technology
Abstract
Purpose: To evaluate the MR findings of gastrointestinal graft-versus-host disease (GVHD) after allogenic bone marrow transplantation. Materials and Methods: Five patients (M:F=3:2, age range: 9-58 years) with suspected gastrointestinal GVHD underwent abdominal MRI, and the findings were evaluated. Because of acute myelocytic leukemia (n=4) or non-Hodgkin's lymphoma (n=1), all had undergone allogenic bone marrow transplantation 2-6 (mean, 3.5) weeks earlier. T2-weighted half-Fourier acquisition snapshot turbo spin-echo, T1-weighted spoiled gradientecho (SGE), and postcontrast T1-weighted SGE MR imaging, with and without fat-suppression, was performed. Results: All five patients showed bowel wall thickening and marked contrast enhancement in the jejunum (n=5), ileum (n=4), duodenum (n=3), sigmoid colon (n=3), gastric antrum (n=2), and rectum (n=2). Bowel wall thickening showed a target appearance in the jejunum (n=2, 40.0%), ileum (n=1, 25.0%), sigmoid colon (n=1, 33.3%), and rectum (n=1, 50.0%), while the remaining cases showed diffuse wall thickening without layering. Small amount of ascites was noted in four patients (80%), and multiple small conglomerated retroperitoneal lymph nodes in three (60%). In all patients, a signal intensity of slightly enlarged liver due to iron overload secondary to multiple blood transfusions, gave rise to decreased signal intensity at both T1-and T2-weighted MR imaging. Conclusion: In patients with GVHD, the commonly noted MR findings were bowel wall thickening with contrast enhancement, ascites and retroperitoneal lymphadenopathy.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Kim, Joo Hee(김주희) ORCID logo https://orcid.org/0000-0001-5383-3602
Yang, Hee Chul(양희철)
Yoo, Hyung Sik(유형식)
Lee, Jong Tae(이종태)
Chung, Jae Joon(정재준) ORCID logo https://orcid.org/0000-0002-7447-1193
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/144734
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