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젊은 알코올 의존 환자에서 신경인지기능의 손상

Other Titles
 Impairment of Neurocognitive Functions in Young Alcohol Dependent Patients: Problem Solving and Executive Functions 
 이충헌  ;  송진관  ;  김지혜  ;  최문종  ;  남궁기 
 Journal of the Korean Neuropsychiatric Association (신경정신의학), Vol.41(6) : 1049-1058, 2002 
Journal Title
 Journal of the Korean Neuropsychiatric Association (신경정신의학) 
Issue Date
젊은 알코올 의존 환자 ; 기억력 ; 문제해결능력 ; 실행기능
Objects: The decline in general neurocognitive functions of alcoholics has been previously reported, especially in the area of memory, problem-solving and executive function which are important for occupational performance or adaptation to enviroment. On the other hand, young alcoholics under the age of 40 with relatively short duration of problem drinking were reported of no significant decline in neurocognitive functions consisting of memory, problem-solving and executive function. The objective of this study is to investigate whether there is a decline in neurocognitive functions around memory, problem-solving and executive function in abstinent young alcoholics. Method: 24 male and female alcohol dependent patients from the age of 19 to 39 years, who were detoxified in the hospotal were recruited as subjects. Normal control group of 20 males and females who matched for age, sex, educational level were selected. Clinical characteristics of the subjects were examined by demographic variables, alcohol history, Beck’s Depression Inventory, Michigan Alcohol Screening Test and Standard Progressive Matrices. Also, subtests of Wechsler Memory Scale-Revised, Block design from the Korean-Wechsler Adult Intelligence, Wisconsin Card Sorting Test were performed in order to evaluate the subjects’ neurocognitive functions. Results: Compared to normal controls, significant decline in neurocognitive functions such as memory, problem-solving and executive function were observed in young alcohol dependent patients with an average age of 32. Parts of the neuropsychological tests showed significant correlation with duration of lifetime drinking and lifetime alcohol consumption. Conclusion: This study shows that, unlike previous reports, decline in memory, problem-solving and executive function occur in young alcoholics as in chronic alcoholics. This implies that young alcoholics can experience difficulty in occupational performance and adaptation to environment, and may be less responsive to treatment due to neurocognitive damage. The results of this study inclicate the importance of early identification, intervention, and planning therapeutic strategies in young alcoholics.
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1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Namkoong, Kee(남궁기) ORCID logo https://orcid.org/0000-0003-1400-8057
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