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Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family

Authors
 Seung Jung Han  ;  Taeksun Song  ;  Yong-Joon Cho  ;  Jong-Seok Kim  ;  Soo Young Choi  ;  Hye-Eun Bang  ;  Jongsik Chun  ;  Gill-Han Bai  ;  Sang-Nae Cho  ;  Sung Jae Shin 
Citation
 STANDARDS IN GENOMIC SCIENCES, Vol.10 : 78, 2015 
Journal Title
 STANDARDS IN GENOMIC SCIENCES 
Issue Date
2015
Keywords
Korean Beijing strain ; M. tuberculosis K complete genome ; Mycobacterium tuberculosis ; Outbreak ; TB Beijing family ; TB clinical strain
Abstract
Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals
Files in This Item:
T201504093.pdf Download
DOI
10.1186/s40793-015-0071-4
Appears in Collections:
5. Research Institutes (연구소) > Institute for Immunology and Immunological Disease (면역질환연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Microbiology (미생물학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jong Seok(김종석)
Shin, Sung Jae(신성재) ORCID logo https://orcid.org/0000-0003-0854-4582
Cho, Sang Nae(조상래)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141639
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