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Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features

 Chae Jung Park  ;  Eun-Kyung Kim  ;  Ha Young Woo  ;  Hee Jung Moon  ;  Jung Hyun Yoon  ;  Min Jung Kim 
 Journal of Breast Cancer, Vol.18(3) : 291-295, 2015 
Journal Title
 Journal of Breast Cancer 
Issue Date
Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)
Yonsei Authors
김민정(Kim, Min Jung) ; 김은경(Kim, Eun-Kyung) ; 문희정(Moon, Hee Jung) ; 박채정(Park, Chae Jung) ; 윤정현(Yoon, Jung Hyun)
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