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Molecular Pathogenesis of Corneal Dystrophies: Schnyder Dystrophy and Granular Corneal Dystrophy type 2

Authors
 Eung Kweon Kim  ;  Hun Lee  ;  Seung-il Choi 
Citation
 Progress in Molecular Biology and Translational Science, Vol.134 : 99-115, 2015 
Journal Title
 Progress in Molecular Biology and Translational Science 
ISSN
 1877-1173 
Issue Date
2015
Abstract
The International Committee for Classification of Corneal Dystrophies (IC3D) provides updated data to ophthalmologists by incorporating traditional definitions of corneal dystrophies with new genetic, clinical, and pathologic information. Recent advances in the genetics of corneal dystrophies facilitate more precise classifications and elucidate each classification's molecular mechanisms. Unfortunately, the molecular mechanisms and underlying pathogenic mechanisms have remained obscure, with the exception of Schnyder corneal dystrophy (CD), granular CD type 2 (GCD2), and Fuch's endothelial CD. Here, we review the pathogenesis of Schnyder CD and GCD2
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141541
DOI
10.1016/bs.pmbts.2015.05.003
Appears in Collections:
1. Journal Papers (연구논문) > 5. Research Institutes (연구소) > Corneal Dystrophy Research Institute (각막이상증연구소)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실)
Yonsei Authors
김응권(Kim, Eung Kweon)
이훈(Lee, Hun)
최승일(Choi, Seung Il)
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Full Text
http://www.sciencedirect.com/science/article/pii/S1877117315000745
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