Cited 13 times in
Is Non-Contrast CT Adequate for the Evaluation of Hepatic Metastasis in Patients Who Cannot Receive Iodinated Contrast Media?
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김명진 | - |
dc.contributor.author | 박미숙 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 정용은 | - |
dc.date.accessioned | 2016-02-04T11:34:17Z | - |
dc.date.available | 2016-02-04T11:34:17Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140721 | - |
dc.description.abstract | OBJECTIVE: To evaluate the appropriateness of follow-up with only non-enhanced CT (NECT) in patients with gastrointestinal cancer. SUBJECTS AND METHODS: This retrospective study included 323 patients with colorectal and gastric cancer who underwent two consecutive CT examinations (CT1 and CT2), including non-contrast and portal venous phase CT images, with an interval of 1 year. Patients were divided into 2 groups: Group A included patients with no hepatic metastasis on CT1 and with or without newly developed metastasis on CT2 to evaluate the diagnostic performance of NECT for detecting newly developed hepatic metastasis; Group B included patients with known hepatic metastasis both on CT1 and CT2 to evaluate the accuracy of NECT for the assessment of hepatic metastasis based on RECIST criteria (version 1.1). Contrast-enhanced CT (CECT) images were considered as reference standards. RESULTS: Group A included 172 patients (M:F = 107:65; mean age, 62.6 years). Among them, 57 patients had 95 metastases (mean size, 2.2 ± 1.3 cm). Per patient and per lesion sensitivity for diagnosing newly developed hepatic metastasis was 56.1-66.7% and 52.6-56.8%, respectively. In terms of small metastases (<1.5 cm), per lesion sensitivity was significantly decreased to 28.1-34.4% (P < 0.05). Metastasis size measurements were significantly smaller on NECT (P < 0.001) compared with reference standards. In Group B, the accuracy of response evaluation based on RECIST criteria was 65.6-72.2%. CONCLUSIONS: NECT showed inadequate diagnostic performances in both detecting newly developed hepatic metastasis and evaluating the response of hepatic metastasis based on RECIST criteria. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | e0134133 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Colorectal Neoplasms/diagnostic imaging | - |
dc.subject.MESH | Colorectal Neoplasms/pathology* | - |
dc.subject.MESH | Contrast Media | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Iodine Radioisotopes | - |
dc.subject.MESH | Liver Neoplasms/diagnostic imaging | - |
dc.subject.MESH | Liver Neoplasms/secondary* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Stomach Neoplasms/diagnostic imaging | - |
dc.subject.MESH | Stomach Neoplasms/pathology* | - |
dc.subject.MESH | Tomography, X-Ray Computed/methods* | - |
dc.title | Is Non-Contrast CT Adequate for the Evaluation of Hepatic Metastasis in Patients Who Cannot Receive Iodinated Contrast Media? | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Yonsei Biomedical Research Center (연세의생명연구원) | - |
dc.contributor.googleauthor | Han Bum Jee | - |
dc.contributor.googleauthor | Min Jung Park | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Mi-Suk Park | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Yong Eun Chung | - |
dc.identifier.doi | 10.1371/journal.pone.0134133 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03312 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A01463 | - |
dc.contributor.localId | A03662 | - |
dc.relation.journalcode | J02540 | - |
dc.identifier.eissn | 1932-6203 | - |
dc.identifier.pmid | 26218533 | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Park, Mi Sook | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Chung, Yong Eun | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | Park, Mi-Suk | - |
dc.contributor.affiliatedAuthor | Chung, Yong Eun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 10 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | e0134133 | - |
dc.identifier.bibliographicCitation | PLOS ONE, Vol.10(7) : e0134133, 2015 | - |
dc.identifier.rimsid | 30267 | - |
dc.type.rims | ART | - |
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