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Impact of temporary opening using a stent retriever on clinical outcome in acute ischemic stroke

DC Field Value Language
dc.contributor.author허지회-
dc.contributor.author김동익-
dc.contributor.author김동준-
dc.contributor.author김병문-
dc.contributor.author김영대-
dc.contributor.author남효석-
dc.contributor.author송동범-
dc.contributor.author유준상-
dc.contributor.author이기정-
dc.contributor.author이혜선-
dc.date.accessioned2016-02-04T11:13:05Z-
dc.date.available2016-02-04T11:13:05Z-
dc.date.issued2015-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139928-
dc.description.abstractBACKGROUND: Stent retriever has a distinct ability to restore blood flow temporarily before achieving final reperfusion. There has been a limited report regarding the clinical impact of it. We investigated if temporary opening of occluded vessels using a stent retriever before final reperfusion might improve clinical outcome in acute ischemic stroke patients who received the endovascular reperfusion treatment. METHODS: We enrolled consecutive ischemic stroke patients who had an initial occlusive lesion in the anterior circulation and achieved final reperfusion (Thrombolysis In Cerebral Infarction [TICI] ≥2) by endovascular treatment. Temporary opening was defined as the presence of ante grade flow (TICI≥2) during deployment of a stent retriever. Favorable outcome was defined as a modified Rankin scale score≤2 at 90 day. RESULTS: A total of 98 patients were included in the study and temporary opening was achieved in 49 (50%). Temporary opening was associated with favorable outcome (odds ratio, 7.825; 95% confidence interval, 1.592-38.461; p = 0.011) in the multivariate analysis. The probability of having a favorable outcome tended to decrease as time from onset to final reperfusion increased in patients without temporary opening. However, this trend was not evident in the patient with temporary opening. The beneficial effect of temporary opening on clinical outcome seemed to be present in patients with good collaterals but not in patients with poor collaterals. CONCLUSIONS: Temporary opening of occluded vessel using a stent retriever may be beneficial for improving clinical outcome in acute ischemic stroke patients.-
dc.description.statementOfResponsibilityopen-
dc.format.extente0124551-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBrain Ischemia/therapy*-
dc.subject.MESHEndovascular Procedures*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHReperfusion-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStents*-
dc.subject.MESHStroke/therapy*-
dc.subject.MESHThrombectomy*-
dc.subject.MESHTreatment Outcome-
dc.titleImpact of temporary opening using a stent retriever on clinical outcome in acute ischemic stroke-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.googleauthorDongbeom Song-
dc.contributor.googleauthorJi Hoe Heo-
dc.contributor.googleauthorDong Ik Kim-
dc.contributor.googleauthorDong Joon Kim-
dc.contributor.googleauthorByung Moon Kim-
dc.contributor.googleauthorKijeong Lee-
dc.contributor.googleauthorJoonsang Yoo-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorHyo Suk Nam-
dc.contributor.googleauthorYoung Dae Kim-
dc.identifier.doi10.1371/journal.pone.0124551-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04369-
dc.contributor.localIdA00408-
dc.contributor.localIdA00410-
dc.contributor.localIdA00498-
dc.contributor.localIdA00702-
dc.contributor.localIdA01273-
dc.contributor.localIdA02017-
dc.contributor.localIdA02513-
dc.contributor.localIdA02696-
dc.contributor.localIdA03312-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid25879929-
dc.contributor.alternativeNameHeo, Ji Hoe-
dc.contributor.alternativeNameKim, Dong Ik-
dc.contributor.alternativeNameKim, Dong Joon-
dc.contributor.alternativeNameKim, Byung Moon-
dc.contributor.alternativeNameKim, Young Dae-
dc.contributor.alternativeNameNam, Hyo Suk-
dc.contributor.alternativeNameSong, Dong Beom-
dc.contributor.alternativeNameYoo, Joon Sang-
dc.contributor.alternativeNameLee, Ki Jeong-
dc.contributor.alternativeNameLee, Hye Sun-
dc.contributor.affiliatedAuthorHeo, Ji Hoe-
dc.contributor.affiliatedAuthorKim, Dong Ik-
dc.contributor.affiliatedAuthorKim, Dong Joon-
dc.contributor.affiliatedAuthorKim, Byung Moon-
dc.contributor.affiliatedAuthorKim, Young Dae-
dc.contributor.affiliatedAuthorNam, Hyo Suk-
dc.contributor.affiliatedAuthorSong, Dong Beom-
dc.contributor.affiliatedAuthorYoo, Joon Sang-
dc.contributor.affiliatedAuthorLee, Ki Jeong-
dc.contributor.affiliatedAuthorLee, Hye Sun-
dc.rights.accessRightsfree-
dc.citation.volume10-
dc.citation.number4-
dc.citation.startPagee0124551-
dc.identifier.bibliographicCitationPLOS ONE, Vol.10(4) : e0124551, 2015-
dc.identifier.rimsid48384-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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