Cited 15 times in
Normal range of hepatic fat fraction on dual- and triple-echo fat quantification MR in children
DC Field | Value | Language |
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dc.contributor.author | 고홍 | - |
dc.contributor.author | 김명준 | - |
dc.contributor.author | 김하얀 | - |
dc.contributor.author | 김현지 | - |
dc.contributor.author | 노윤호 | - |
dc.contributor.author | 신현주 | - |
dc.contributor.author | 이미정 | - |
dc.date.accessioned | 2016-02-04T10:59:04Z | - |
dc.date.available | 2016-02-04T10:59:04Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139410 | - |
dc.description.abstract | OBJECTIVES: To evaluate hepatic fat fraction on dual- and triple-echo gradient-recalled echo MRI sequences in healthy children. MATERIALS AND METHODS: We retrospectively reviewed the records of children in a medical check-up clinic from May 2012 to November 2013. We excluded children with abnormal laboratory findings or those who were overweight. Hepatic fat fraction was measured on dual- and triple-echo sequences using 3T MRI. We compared fat fractions using the Wilcoxon signed rank test and the Bland-Altman 95% limits of agreement. The correlation between fat fractions and clinical and laboratory findings was evaluated using Spearman's correlation test, and the cut-off values of fat fractions for diagnosing fatty liver were obtained from reference intervals. RESULTS: In 54 children (M:F = 26:28; 5-15 years; mean 9 years), the dual fat fraction (0.1-8.0%; median 1.6%) was not different from the triple fat fraction (0.4-6.5%; median 2.7%) (p = 0.010). The dual- and triple-echo fat fractions showed good agreement using a Bland-Altman plot (-0.6 ± 2.8%). Eight children (14.8%) on dual-echo sequences and six (11.1%) on triple-echo sequences had greater than 5% fat fraction. From these children, six out of eight children on dual-echo sequences and four out of six children on triple-echo sequences had a 5-6% hepatic fat fraction. When using a cut-off value of a 6% fat fraction derived from a reference interval, only 3.7% of children were diagnosed with fatty liver. There was no significant correlation between clinical and laboratory findings with dual and triple-echo fat fractions. CONCLUSIONS: Dual fat fraction was not different from triple fat fraction. We suggest a cut-off value of a 6% fat fraction is more appropriate for diagnosing fatty liver on both dual- and triple-echo sequences in children. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | e0117480 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adipose Tissue/diagnostic imaging* | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Echo-Planar Imaging* | - |
dc.subject.MESH | Fatty Liver/diagnostic imaging* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver/diagnostic imaging* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Radiography | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Normal range of hepatic fat fraction on dual- and triple-echo fat quantification MR in children | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Hyun Joo Shin | - |
dc.contributor.googleauthor | Hyun Gi Kim | - |
dc.contributor.googleauthor | Myung-Joon Kim | - |
dc.contributor.googleauthor | Hong Koh | - |
dc.contributor.googleauthor | Ha Yan Kim | - |
dc.contributor.googleauthor | Yun Ho Roh | - |
dc.contributor.googleauthor | Mi-Jung Lee | - |
dc.identifier.doi | 10.1371/journal.pone.0117480 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02774 | - |
dc.contributor.localId | A01091 | - |
dc.contributor.localId | A00156 | - |
dc.contributor.localId | A00425 | - |
dc.contributor.localId | A01139 | - |
dc.contributor.localId | A01287 | - |
dc.contributor.localId | A02178 | - |
dc.relation.journalcode | J02540 | - |
dc.identifier.eissn | 1932-6203 | - |
dc.identifier.pmid | 25659155 | - |
dc.contributor.alternativeName | Koh, Hong | - |
dc.contributor.alternativeName | Kim, Myung Joon | - |
dc.contributor.alternativeName | Kim, Ha Yan | - |
dc.contributor.alternativeName | Kim, Hyun Gi | - |
dc.contributor.alternativeName | Roh, Yun Ho | - |
dc.contributor.alternativeName | Shin, Hyun Joo | - |
dc.contributor.alternativeName | Lee, Mi Jung | - |
dc.contributor.affiliatedAuthor | Lee, Mi Jung | - |
dc.contributor.affiliatedAuthor | Kim, Ha Yan | - |
dc.contributor.affiliatedAuthor | Koh, Hong | - |
dc.contributor.affiliatedAuthor | Kim, Myung Joon | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Gi | - |
dc.contributor.affiliatedAuthor | Roh, Yun Ho | - |
dc.contributor.affiliatedAuthor | Shin, Hyun Joo | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 10 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | e0117480 | - |
dc.identifier.bibliographicCitation | PLOS ONE, Vol.10(2) : e0117480, 2015 | - |
dc.identifier.rimsid | 55377 | - |
dc.type.rims | ART | - |
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