Cited 27 times in
Prognostic value of coronary computed tomography angiography in stroke patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김영진 | - |
dc.contributor.author | 서영주 | - |
dc.contributor.author | 이계호 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 이혜정 | - |
dc.contributor.author | 장혁재 | - |
dc.contributor.author | 최병욱 | - |
dc.contributor.author | 허진 | - |
dc.contributor.author | 홍새롬 | - |
dc.contributor.author | 홍유진 | - |
dc.date.accessioned | 2016-02-04T10:57:58Z | - |
dc.date.available | 2016-02-04T10:57:58Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139370 | - |
dc.description.abstract | OBJECTIVE: The predictive value of coronary computed tomography angiography (CCTA) in stroke patients has not yet been established. We investigated the prognostic value of coronary artery disease (CAD) detection by CCTA, and determined the incremental risk stratification benefit of CCTA findings as compared to coronary artery calcium scores (CACS) in ischemic stroke patients without chest pain. METHODS: Among 914 consecutive ischemic stroke patients, 317 (68.5% were male with a mean age of 64 years) who had at least one clinical risk factor for CAD without chest pain were prospectively enrolled to undergo CCTA. CT images were assessed for CAC, presence of CAD and extent of CAD. The primary endpoint was major adverse cardiac events (MACEs) defined as cardiac death, non-fatal myocardial infarction, unstable angina requiring hospitalization, or revascularization after 90 days from index CCTA. RESULTS: The prevalence of CAC ≥1 was 73.1% (232/317) and the average CACS was 346.6 ± 693.5 (Agatston unit). During the median follow-up period of 409 days, there were a total of 26 MACEs. Both CACS [CAC (101-400, and >400)] and CCTA findings [presence of obstructive CAD, 1-vessel disease (VD), 2-VD, and 3-VD] independently stratified risk of future MACEs (all p < 0.05). The time-dependent receiver operating characteristic curve analysis revealed that CAD findings (presence of obstructive CAD and number of involved vessels) based on CCTA improved risk stratification beyond clinical risk factors and CACS (iAUC: 0.863 vs 0.752, p < 0.05). CONCLUSION: In ischemic stroke patients without chest pain, CCTA findings of CAD provide additional risk-discrimination over CACS. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 271~277 | - |
dc.relation.isPartOf | ATHEROSCLEROSIS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angina, Unstable/mortality | - |
dc.subject.MESH | Angina, Unstable/therapy | - |
dc.subject.MESH | Area Under Curve | - |
dc.subject.MESH | Coronary Angiography/methods* | - |
dc.subject.MESH | Coronary Artery Disease/diagnostic imaging* | - |
dc.subject.MESH | Coronary Artery Disease/mortality | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hospitalization | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myocardial Infarction/mortality | - |
dc.subject.MESH | Myocardial Infarction/therapy | - |
dc.subject.MESH | Myocardial Revascularization | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Stroke/diagnostic imaging* | - |
dc.subject.MESH | Stroke/mortality | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Tomography, X-Ray Computed* | - |
dc.subject.MESH | Vascular Calcification/diagnostic imaging | - |
dc.subject.MESH | Vascular Calcification/mortality | - |
dc.title | Prognostic value of coronary computed tomography angiography in stroke patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jin Hur | - |
dc.contributor.googleauthor | Kye Ho Lee | - |
dc.contributor.googleauthor | Sae Rom Hong | - |
dc.contributor.googleauthor | Young Joo Suh | - |
dc.contributor.googleauthor | Yoo Jin Hong | - |
dc.contributor.googleauthor | Hye-Jeong Lee | - |
dc.contributor.googleauthor | Young Jin Kim | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Byoung Wook Choi | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2014.10.102 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01892 | - |
dc.contributor.localId | A02665 | - |
dc.contributor.localId | A03490 | - |
dc.contributor.localId | A04059 | - |
dc.contributor.localId | A04370 | - |
dc.contributor.localId | A04396 | - |
dc.contributor.localId | A04422 | - |
dc.contributor.localId | A03311 | - |
dc.contributor.localId | A00727 | - |
dc.contributor.localId | A03320 | - |
dc.relation.journalcode | J00260 | - |
dc.identifier.eissn | 1879-1484 | - |
dc.identifier.pmid | 25544177 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0021915014015573 | - |
dc.subject.keyword | Coronary artery disease (CAD) | - |
dc.subject.keyword | Coronary computed tomography angiography (CCTA) | - |
dc.subject.keyword | Major adverse cardiac events (MACE) | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Stroke | - |
dc.contributor.alternativeName | Kim, Young Jin | - |
dc.contributor.alternativeName | Suh, Young Joo | - |
dc.contributor.alternativeName | Lee, Kye Ho | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Lee, Hye Jeong | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.alternativeName | Choi, Byoung Wook | - |
dc.contributor.alternativeName | Hur, Jin | - |
dc.contributor.alternativeName | Hong, Sae Rom | - |
dc.contributor.alternativeName | Hong, Yoo Jin | - |
dc.contributor.affiliatedAuthor | Suh, Young Joo | - |
dc.contributor.affiliatedAuthor | Lee, Kye Ho | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Choi, Byoung Wook | - |
dc.contributor.affiliatedAuthor | Hur, Jin | - |
dc.contributor.affiliatedAuthor | Hong, Sae Rom | - |
dc.contributor.affiliatedAuthor | Hong, Yoo Jin | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.contributor.affiliatedAuthor | Kim, Young Jin | - |
dc.contributor.affiliatedAuthor | Lee, Hye Jeong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 238 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 271 | - |
dc.citation.endPage | 277 | - |
dc.identifier.bibliographicCitation | ATHEROSCLEROSIS, Vol.238(2) : 271-277, 2015 | - |
dc.identifier.rimsid | 39407 | - |
dc.type.rims | ART | - |
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