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Effects of blood lead levels on airflow limitations in Korean adults: findings from the 5th KNHNES 2011

Authors
 Hye Kyung Chung  ;  Yoon Soo Chang  ;  Chul Woo Ahn 
Citation
 Environmental Research, Vol.136 : 274-279, 2015 
Journal Title
 Environmental Research 
ISSN
 0013-9351 
Issue Date
2015
Abstract
This study aimed to examine whether blood levels of heavy metals, such as lead, mercury and cadmium, are related with pulmonary function in Korean adults. This investigation included 870 Korean adults (≥ 40 years) who received pulmonary function testing in the Korea National Health and Nutrition Examination Survey (KNHANES) V-2, 2011. Data of blood levels of heavy metals, pulmonary function tests and anthropometric measurements were acquired. Blood lead levels showed inverse correlations with the FEV1/FVC ratio before (r = -0.276, p < 0.001) and after adjustment of multiple compounding factors (r = -0.115, p = 0.001). A logistic multiple regression analysis revealed that blood lead levels were a significant influencing factor for the FEV1/FVC ratio (β = -0.017, p = 0.001, adjusted R(2) = 0.267). The odds ratios (ORs) for the FEV1/FVC ratio were significantly lower in the highest tertile group of the blood lead levels than in the lowest tertile group in Model 1 (OR = 0.007, 95% CI = 0.000-0.329) and Model 2 (OR = 0.006, 95% CI = 0.000-0.286). These findings imply that environmental exposure to lead might be an important factor that may cause airflow limitations in Korean adults.
Full Text
http://www.sciencedirect.com/science/article/pii/S0013935114003910
DOI
10.1016/j.envres.2014.10.027
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Institute for Vascular and Metabolic Research (혈관대사연구소) > 1. Journal Papers
Yonsei Authors
안철우(Ahn, Chul Woo) ORCID logo https://orcid.org/0000-0003-3733-7486
장윤수(Chang, Yoon Soo) ORCID logo https://orcid.org/0000-0003-3340-4223
정혜경(Chung, Hye Kyung)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139229
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