0 357

Cited 15 times in

Fabrication of bioactive, antibacterial TiO2 nanotube surfaces, coated with magnetron sputtered Ag nanostructures for dental applications.

Authors
 Soo Hyuk Uhm  ;  Sang Bae Lee  ;  Doo Hoon Song  ;  Jae Sung Kwon  ;  Jeon Geon Han  ;  Kyoung Nam Kim 
Citation
 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, Vol.14(10) : 7847-7854, 2014 
Journal Title
 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 
ISSN
 1533-4880 
Issue Date
2014
MeSH
Animals ; Anti-Bacterial Agents/chemistry* ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/toxicity ; Cell Line ; Coated Materials, Biocompatible/chemistry* ; Coated Materials, Biocompatible/pharmacology ; Coated Materials, Biocompatible/toxicity ; Dental Implants* ; Male ; Metal Nanoparticles/chemistry* ; Mice ; Nanotubes/chemistry* ; Pressure ; Silver/chemistry* ; Staphylococcus aureus/drug effects ; Surface Properties ; Titanium/chemistry* ; Titanium/pharmacology ; Titanium/toxicity
Abstract
We investigated whether a silver coating on an anodic oxidized titania (TiO2) nanotube surface would be useful for preventing infections in dental implants. We used a magnetron sputtering process to deposit Ag nanoparticles onto a TiO2 surface. We studied different sputtering input power densities and maintained other parameters constant. We used scanning electron microscopy, X-ray diffraction, and contact angle measurements to characterize the coated surfaces. Staphylococcus aureus was used to evaluate antibacterial activity. The X-ray diffraction analysis showed peaks that corresponded to metallic Ag, Ti, O, and biocompatible anatase phase TiO2 on the examined surfaces. The contact angles of the Ag nanoparticle-loaded surfaces were significantly lower at 2.5 W/cm2 input power under pulsed direct current mode compared to commercial, untreated Ti surfaces. In vitro antibacterial analysis indicated that a significantly reduced number of S. aureus were detected on an Ag nanoparticle-loaded TiO2 nanotube surface compared to control untreated surfaces. No cytotoxicity was noted, except in the group treated with 5 W/cm2 input power density, which was the highest input of power density we tested for the magnetron sputtering process. Overall, we concluded that it was feasible to create antibacterial Ag nanoparticle-loaded titanium nanotube surfaces with magnetron sputtering.
Full Text
http://www.ingentaconnect.com/content/asp/jnn/2014/00000014/00000010/art00085
DOI
10.1166/jnn.2014.9412
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Jae-Sung(권재성) ORCID logo https://orcid.org/0000-0001-9803-7730
Kim, Kyoung Nam(김경남)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/138263
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse