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Fabrication of bioactive, antibacterial TiO2 nanotube surfaces, coated with magnetron sputtered Ag nanostructures for dental applications.

DC Field Value Language
dc.contributor.author권재성-
dc.contributor.author김경남-
dc.date.accessioned2015-12-28T10:53:58Z-
dc.date.available2015-12-28T10:53:58Z-
dc.date.issued2014-
dc.identifier.issn1533-4880-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/138263-
dc.description.abstractWe investigated whether a silver coating on an anodic oxidized titania (TiO2) nanotube surface would be useful for preventing infections in dental implants. We used a magnetron sputtering process to deposit Ag nanoparticles onto a TiO2 surface. We studied different sputtering input power densities and maintained other parameters constant. We used scanning electron microscopy, X-ray diffraction, and contact angle measurements to characterize the coated surfaces. Staphylococcus aureus was used to evaluate antibacterial activity. The X-ray diffraction analysis showed peaks that corresponded to metallic Ag, Ti, O, and biocompatible anatase phase TiO2 on the examined surfaces. The contact angles of the Ag nanoparticle-loaded surfaces were significantly lower at 2.5 W/cm2 input power under pulsed direct current mode compared to commercial, untreated Ti surfaces. In vitro antibacterial analysis indicated that a significantly reduced number of S. aureus were detected on an Ag nanoparticle-loaded TiO2 nanotube surface compared to control untreated surfaces. No cytotoxicity was noted, except in the group treated with 5 W/cm2 input power density, which was the highest input of power density we tested for the magnetron sputtering process. Overall, we concluded that it was feasible to create antibacterial Ag nanoparticle-loaded titanium nanotube surfaces with magnetron sputtering.-
dc.description.statementOfResponsibilityopen-
dc.format.extent7847~7854-
dc.relation.isPartOfJOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHAnti-Bacterial Agents/chemistry*-
dc.subject.MESHAnti-Bacterial Agents/pharmacology-
dc.subject.MESHAnti-Bacterial Agents/toxicity-
dc.subject.MESHCell Line-
dc.subject.MESHCoated Materials, Biocompatible/chemistry*-
dc.subject.MESHCoated Materials, Biocompatible/pharmacology-
dc.subject.MESHCoated Materials, Biocompatible/toxicity-
dc.subject.MESHDental Implants*-
dc.subject.MESHMale-
dc.subject.MESHMetal Nanoparticles/chemistry*-
dc.subject.MESHMice-
dc.subject.MESHNanotubes/chemistry*-
dc.subject.MESHPressure-
dc.subject.MESHSilver/chemistry*-
dc.subject.MESHStaphylococcus aureus/drug effects-
dc.subject.MESHSurface Properties-
dc.subject.MESHTitanium/chemistry*-
dc.subject.MESHTitanium/pharmacology-
dc.subject.MESHTitanium/toxicity-
dc.titleFabrication of bioactive, antibacterial TiO2 nanotube surfaces, coated with magnetron sputtered Ag nanostructures for dental applications.-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Dental Engineering (치과생체재료공학)-
dc.contributor.googleauthorSoo Hyuk Uhm-
dc.contributor.googleauthorSang Bae Lee-
dc.contributor.googleauthorDoo Hoon Song-
dc.contributor.googleauthorJae Sung Kwon-
dc.contributor.googleauthorJeon Geon Han-
dc.contributor.googleauthorKyoung Nam Kim-
dc.identifier.doi10.1166/jnn.2014.9412-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00247-
dc.contributor.localIdA00292-
dc.relation.journalcodeJ01615-
dc.identifier.eissn1533-4899-
dc.identifier.pmid25942879-
dc.identifier.urlhttp://www.ingentaconnect.com/content/asp/jnn/2014/00000014/00000010/art00085-
dc.contributor.alternativeNameKwon, Jae Sung-
dc.contributor.alternativeNameKim, Kyoung Nam-
dc.contributor.affiliatedAuthorKwon, Jae Sung-
dc.contributor.affiliatedAuthorKim, Kyoung Nam-
dc.rights.accessRightsfree-
dc.citation.volume14-
dc.citation.number10-
dc.citation.startPage7847-
dc.citation.endPage7854-
dc.identifier.bibliographicCitationJOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, Vol.14(10) : 7847-7854, 2014-
dc.identifier.rimsid52762-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers

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